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SYBX

Synlogic
SYBX

Delisted

SYBX was delisted on the 20th of January, 2026.

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52 hedge funds and large institutions have $102M invested in Synlogic in 2022 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 11 increasing their positions, 15 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

0.09% less ownership

Funds ownership: 4.14% → 4.05% (-0.09%)

2% less capital invested

Capital invested by funds: $105M → $102M (-$2.36M)

16% less funds holding

Funds holding: 62 → 52 (-10)

26% less call options, than puts

Call options by funds: $14K | Put options by funds: $19K

27% less repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 15

67% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 15

Holders
52
Holders Change
-10
Holders Change %
-16.13%
% of All Funds
0.82%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.03%
New
5
Increased
11
Reduced
15
Closed
15
Calls
$14K
Puts
$19K
Net Calls
-$5K
Net Calls Change
+$5K

Top Buyers

Rank Fund Capital Flow
1
OM
Opaleye Management
Massachusetts
+$279K
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$162K
3
Alyeska Investment Group
Alyeska Investment Group
Illinois
+$154K
4
Geode Capital Management
Geode Capital Management
Massachusetts
+$105K
5
State Street
State Street
Massachusetts
+$86.2K

Top Sellers

Rank Fund Capital Flow
1
Two Sigma Advisers
Two Sigma Advisers
New York
-$453K
2
Two Sigma Investments
Two Sigma Investments
New York
-$449K
3
Millennium Management
Millennium Management
New York
-$448K
4
TCM
Triumph Capital Management
Colorado
-$202K
5
HCA
Harbor Capital Advisors
Illinois
-$171K
Name Holding Trade Value Shares
Change 		Change in
Stake
Wells Fargo
51
Wells Fargo
California
$1K – – –
TCM
52
Triumph Capital Management
Colorado
– -$202K -5,573 Closed
JF
53
Jump Financial
Illinois
– -$91K -2,513 Closed
Jacobs Levy Equity Management
54
Jacobs Levy Equity Management
New Jersey
– -$46K -1,265 Closed
PPA
55
Parametric Portfolio Associates
Washington
– -$31K -859 Closed
Citadel Advisors
56
Citadel Advisors
Florida
– -$27K -753 Closed
Janney Montgomery Scott
57
Janney Montgomery Scott
Pennsylvania
– -$27K -733 Closed
ECM
58
ExodusPoint Capital Management
New York
– -$26K -728 Closed
Bank of America
59
Bank of America
North Carolina
– -$26K -724 Closed
Bank Julius Baer & Co
60
Bank Julius Baer & Co
Switzerland
– -$19K -533 Closed
Simplex Trading
61
Simplex Trading
Illinois
– -$10.2K -326 Closed
TCWM
62
Total Clarity Wealth Management
Illinois
– -$2K -67 Closed
HNWAG
63
High Net Worth Advisory Group
Florida
– -$1K -33 Closed
CAPTRUST Financial Advisors
64
CAPTRUST Financial Advisors
North Carolina
– -$1K -16 Closed
Federated Hermes
65
Federated Hermes
Pennsylvania
– -$1K -15 Closed
1 2
3

SYBX Hedge Fund Activity: Q1 2022 in Review

52 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q1 2022, worth a combined $102M — down 2.2% from $105M a quarter earlier.

Sellers outnumbered buyers: 15 funds closed out of SYBX and 5 opened new positions — a net loss of 10 holders — while 15 trimmed existing stakes and 11 added.

The largest buyer was Opaleye Management, adding an estimated $279K. The largest seller was Two Sigma Advisers, cutting an estimated $453K.

  • 52 institutional investors held Synlogic (SYBX) as of Q1 2022, down from 62 in Q4 2021.
  • Funds reported $102M of Synlogic stock for Q1 2022, down 2.2% quarter-over-quarter.
  • 5 funds opened new Synlogic positions in Q1 2022 and 15 closed out, a net change of -10 holders.
  • The largest Synlogic buyer in Q1 2022 was Opaleye Management, an estimated $279K added.
  • The largest Synlogic seller in Q1 2022 was Two Sigma Advisers, an estimated $453K sold.

Based on aggregated 13F filings for Q1 2022.