Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
55 hedge funds and large institutions have $65.8M invested in Synlogic in 2021 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 11 increasing their positions, 15 reducing their positions, and 10 closing their positions.
90% more first-time investments, than exits
New positions opened: 19 | Existing positions closed: 10
77% more capital invested
Capital invested by funds: $37.1M → $65.8M (+$28.7M)
17% more funds holding
Funds holding: 47 → 55 (+8)
0.2% less ownership
Funds ownership: 3.29% → 3.09% (-0.2%)
2% less call options, than puts
Call options by funds: $133K | Put options by funds: $136K
27% less repeat investments, than reductions
Existing positions increased: 11 | Existing positions reduced: 15
33% less funds holding in top 10
Funds holding in top 10: 3 → 2 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
IC
Ikarian Capital
Dallas,
Texas
|
+$5.67M |
| 2 |
GGHC
Gilder Gagnon Howe & Co
New York
|
+$5.65M |
| 3 |
RA
Royce & Associates
New York
|
+$1.84M |
| 4 |
BFM
Boothbay Fund Management
New York
|
+$725K |
| 5 |
Two Sigma Advisers
New York
|
+$703K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
D.E. Shaw & Co
New York
|
-$655K |
| 2 |
Acadian Asset Management
Boston,
Massachusetts
|
-$389K |
| 3 |
Morgan Stanley
New York
|
-$206K |
| 4 |
Renaissance Technologies
New York
|
-$135K |
| 5 |
Millennium Management
New York
|
-$126K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
51
BNP Paribas Financial Markets
Paris,
France
| $1.8K | -$57 | -1 | -3% |
|
52
Barclays
London,
United Kingdom
| $1K | +$1.08K | +19 | New |
|
|
53
Millennium Management
New York
| – | -$126K | -3,886 | Closed |
|
54
Verition Fund Management
Greenwich,
Connecticut
| – | -$53K | -1,647 | Closed |
|
55
Jane Street
New York
| – | -$39K | -1,219 | Closed |
|
|
RJA
56
Raymond James & Associates
St Petersburg,
Florida
| – | -$36K | -1,100 | Closed |
|
|
1WM
57
1900 Wealth Management
San Antonio,
Texas
| – | -$35K | -1,087 | Closed |
|
|
LFF
58
Level Four Financial
Dallas,
Texas
| – | -$35K | -1,067 | Closed |
|
59
Qube Research & Technologies (QRT)
London,
United Kingdom
| – | -$24K | -742 | Closed |
|
|
FQ
60
First Quadrant
Glendale,
California
| – | -$19K | -576 | Closed |
|
|
TRCT
61
Tower Research Capital (TRC)
New York
| – | -$18K | -540 | Closed |
|
62
Fidelity Investments
Boston,
Massachusetts
| – | -$2K | -60 | Closed |
|
63
JP Morgan Chase
New York
| – | -$1.37K | -24 | -96% |
|
SYBX Hedge Fund Activity: Q1 2021 in Review
55 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q1 2021, worth a combined $65.8M — up 77% from $37.1M a quarter earlier.
Buyers outnumbered sellers: 19 funds opened new SYBX positions and 10 closed out — a net gain of 9 holders — while 11 added to existing stakes and 15 trimmed.
The largest buyer was Ikarian Capital, opening a new position worth an estimated $5.67M. The largest seller was D.E. Shaw & Co, cutting an estimated $655K.
- 55 institutional investors held Synlogic (SYBX) as of Q1 2021, up from 47 in Q4 2020.
- Funds reported $65.8M of Synlogic stock for Q1 2021, up 77% quarter-over-quarter.
- 19 funds opened new Synlogic positions in Q1 2021 and 10 closed out, a net change of +9 holders.
- The largest Synlogic buyer in Q1 2021 was Ikarian Capital, an estimated $5.67M added.
- The largest Synlogic seller in Q1 2021 was D.E. Shaw & Co, an estimated $655K sold.
Based on aggregated 13F filings for Q1 2021.