Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
24 hedge funds and large institutions have $18.2M invested in Synlogic in 2023 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 9 increasing their positions, 5 reducing their positions, and 7 closing their positions.
147% more capital invested
Capital invested by funds: $7.34M → $18.2M (+$10.8M)
80% more repeat investments, than reductions
Existing positions increased: 9 | Existing positions reduced: 5
7.2% less ownership
Funds ownership: 58.55% → 51.34% (-7.2%)
14% less funds holding
Funds holding: 28 → 24 (-4)
43% less first-time investments, than exits
New positions opened: 4 | Existing positions closed: 7
50% less funds holding in top 10
Funds holding in top 10: 2 → 1 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
NMC
NEA Management Company
Timonium,
Maryland
|
+$6.68M |
| 2 |
AC
Armistice Capital
New York
|
+$1.15M |
| 3 |
Renaissance Technologies
New York
|
+$138K |
| 4 |
Vanguard Group
Malvern,
Pennsylvania
|
+$98.3K |
| 5 |
Geode Capital Management
Boston,
Massachusetts
|
+$35.7K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
O
OrbiMed
New York
|
-$1.13M |
| 2 |
Fidelity Investments
Boston,
Massachusetts
|
-$982K |
| 3 |
Alyeska Investment Group
Chicago,
Illinois
|
-$284K |
| 4 |
UOC
UBS O'Connor
Chicago,
Illinois
|
-$114K |
| 5 |
SI
Sofinnova Investments
Menlo Park,
California
|
-$108K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
UOC
26
UBS O'Connor
Chicago,
Illinois
| – | -$114K | -40,548 | Closed |
|
|
SI
27
Sofinnova Investments
Menlo Park,
California
| – | -$108K | -38,331 | Closed |
|
|
WG
28
Winton Group
London,
United Kingdom
| – | -$34.8K | -12,401 | Closed |
|
29
Goldman Sachs
New York
| – | -$30.9K | -11,012 | Closed |
|
30
Osaic Holdings
Scottsdale,
Arizona
| – | -$9.11K | -3,245 | Closed |
|
31
PNC Financial Services Group
Pittsburgh,
Pennsylvania
| – | -$1.31K | -466 | Closed |
|
SYBX Hedge Fund Activity: Q4 2023 in Review
24 of the 6,859 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q4 2023, worth a combined $18.2M — up 147% from $7.34M a quarter earlier.
Sellers outnumbered buyers: 7 funds closed out of SYBX and 4 opened new positions — a net loss of 3 holders — while 5 trimmed existing stakes and 9 added.
The largest buyer was NEA Management Company, adding an estimated $6.68M. The largest seller was OrbiMed, exiting entirely with an estimated $1.13M sold.
- 24 institutional investors held Synlogic (SYBX) as of Q4 2023, down from 28 in Q3 2023.
- Funds reported $18.2M of Synlogic stock for Q4 2023, up 147% quarter-over-quarter.
- 4 funds opened new Synlogic positions in Q4 2023 and 7 closed out, a net change of -3 holders.
- The largest Synlogic buyer in Q4 2023 was NEA Management Company, an estimated $6.68M added.
- The largest Synlogic seller in Q4 2023 was OrbiMed, an estimated $1.13M sold.
Based on aggregated 13F filings for Q4 2023.