Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
51 hedge funds and large institutions have $40M invested in Synlogic in 2022 Q2 according to their latest regulatory filings, with 5 funds opening new positions, 14 increasing their positions, 16 reducing their positions, and 6 closing their positions.
400% more call options, than puts
Call options by funds: $5K | Put options by funds: $1K
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
0.18% less ownership
Funds ownership: 4.05% → 3.87% (-0.18%)
2% less funds holding
Funds holding: 52 → 51 (-1)
13% less repeat investments, than reductions
Existing positions increased: 14 | Existing positions reduced: 16
17% less first-time investments, than exits
New positions opened: 5 | Existing positions closed: 6
61% less capital invested
Capital invested by funds: $102M → $40M (-$62.5M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Alyeska Investment Group
Chicago,
Illinois
|
+$875K |
| 2 |
UOC
UBS O'Connor
Chicago,
Illinois
|
+$783K |
| 3 |
Millennium Management
New York
|
+$68K |
| 4 |
State Street
Boston,
Massachusetts
|
+$38.2K |
| 5 |
BlackRock
New York
|
+$36.8K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
OM
Opaleye Management
Boston,
Massachusetts
|
-$2.36M |
| 2 |
SCM
Stonepine Capital Management
Bend,
Oregon
|
-$1.4M |
| 3 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$1.21M |
| 4 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$221K |
| 5 |
UBS Group
Zurich,
Switzerland
|
-$84K |
SYBX Hedge Fund Activity: Q2 2022 in Review
51 of the 5,936 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q2 2022, worth a combined $40M — down 61% from $102M a quarter earlier.
Sellers outnumbered buyers: 6 funds closed out of SYBX and 5 opened new positions — a net loss of 1 holder — while 16 trimmed existing stakes and 14 added.
The largest buyer was Alyeska Investment Group, adding an estimated $875K. The largest seller was Opaleye Management, exiting entirely with an estimated $2.36M sold.
- 51 institutional investors held Synlogic (SYBX) as of Q2 2022, down from 52 in Q1 2022.
- Funds reported $40M of Synlogic stock for Q2 2022, down 61% quarter-over-quarter.
- 5 funds opened new Synlogic positions in Q2 2022 and 6 closed out, a net change of -1 holder.
- The largest Synlogic buyer in Q2 2022 was Alyeska Investment Group, an estimated $875K added.
- The largest Synlogic seller in Q2 2022 was Opaleye Management, an estimated $2.36M sold.
Based on aggregated 13F filings for Q2 2022.