Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
69 hedge funds and large institutions have $134M invested in Synlogic in 2021 Q3 according to their latest regulatory filings, with 14 funds opening new positions, 18 increasing their positions, 20 reducing their positions, and 4 closing their positions.
250% more first-time investments, than exits
New positions opened: 14 | Existing positions closed: 4
17% more capital invested
Capital invested by funds: $115M → $134M (+$19M)
15% more funds holding
Funds holding: 60 → 69 (+9)
0.59% more ownership
Funds ownership: 3.75% → 4.34% (+0.59%)
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
10% less repeat investments, than reductions
Existing positions increased: 18 | Existing positions reduced: 20
54% less call options, than puts
Call options by funds: $25K | Put options by funds: $54K
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
+$20.8M |
| 2 |
O
OrbiMed
New York
|
+$7.27M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$7.01M |
| 4 |
LGM
Logos Global Management
San Francisco,
California
|
+$4.67M |
| 5 |
Alyeska Investment Group
Chicago,
Illinois
|
+$3.91M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
GGHC
Gilder Gagnon Howe & Co
New York
|
-$3.59M |
| 2 |
Two Sigma Advisers
New York
|
-$887K |
| 3 |
Dimensional Fund Advisors
Austin,
Texas
|
-$744K |
| 4 |
Two Sigma Investments
New York
|
-$685K |
| 5 |
Renaissance Technologies
New York
|
-$235K |
SYBX Hedge Fund Activity: Q3 2021 in Review
69 of the 5,712 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q3 2021, worth a combined $134M — up 17% from $115M a quarter earlier.
Buyers outnumbered sellers: 14 funds opened new SYBX positions and 4 closed out — a net gain of 10 holders — while 18 added to existing stakes and 20 trimmed.
The largest buyer was RA Capital Management, opening a new position worth an estimated $20.8M. The largest seller was Gilder Gagnon Howe & Co, cutting an estimated $3.59M.
- 69 institutional investors held Synlogic (SYBX) as of Q3 2021, up from 60 in Q2 2021.
- Funds reported $134M of Synlogic stock for Q3 2021, up 17% quarter-over-quarter.
- 14 funds opened new Synlogic positions in Q3 2021 and 4 closed out, a net change of +10 holders.
- The largest Synlogic buyer in Q3 2021 was RA Capital Management, an estimated $20.8M added.
- The largest Synlogic seller in Q3 2021 was Gilder Gagnon Howe & Co, an estimated $3.59M sold.
Based on aggregated 13F filings for Q3 2021.