Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
60 hedge funds and large institutions have $115M invested in Synlogic in 2021 Q2 according to their latest regulatory filings, with 12 funds opening new positions, 16 increasing their positions, 17 reducing their positions, and 7 closing their positions.
74% more capital invested
Capital invested by funds: $65.8M → $115M (+$48.8M)
71% more first-time investments, than exits
New positions opened: 12 | Existing positions closed: 7
9% more funds holding
Funds holding: 55 → 60 (+5)
0.66% more ownership
Funds ownership: 3.09% → 3.75% (+0.66%)
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
6% less repeat investments, than reductions
Existing positions increased: 16 | Existing positions reduced: 17
89% less call options, than puts
Call options by funds: $17K | Put options by funds: $160K
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
+$28.6M |
| 2 |
O
OrbiMed
New York
|
+$6.07M |
| 3 |
Vanguard Group
Malvern,
Pennsylvania
|
+$3.23M |
| 4 |
Alyeska Investment Group
Chicago,
Illinois
|
+$2.91M |
| 5 |
LP
LMR Partners
London,
United Kingdom
|
+$1.09M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
IC
Ikarian Capital
Dallas,
Texas
|
-$2.34M |
| 2 |
GGHC
Gilder Gagnon Howe & Co
New York
|
-$623K |
| 3 |
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
-$608K |
| 4 |
Squarepoint
New York
|
-$312K |
| 5 |
Renaissance Technologies
New York
|
-$180K |
SYBX Hedge Fund Activity: Q2 2021 in Review
60 of the 5,745 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q2 2021, worth a combined $115M — up 74% from $65.8M a quarter earlier.
Buyers outnumbered sellers: 12 funds opened new SYBX positions and 7 closed out — a net gain of 5 holders — while 16 added to existing stakes and 17 trimmed.
The largest buyer was Fidelity Investments, opening a new position worth an estimated $28.6M. The largest seller was Ikarian Capital, cutting an estimated $2.34M.
- 60 institutional investors held Synlogic (SYBX) as of Q2 2021, up from 55 in Q1 2021.
- Funds reported $115M of Synlogic stock for Q2 2021, up 74% quarter-over-quarter.
- 12 funds opened new Synlogic positions in Q2 2021 and 7 closed out, a net change of +5 holders.
- The largest Synlogic buyer in Q2 2021 was Fidelity Investments, an estimated $28.6M added.
- The largest Synlogic seller in Q2 2021 was Ikarian Capital, an estimated $2.34M sold.
Based on aggregated 13F filings for Q2 2021.