|
1
|
|
$55.1M
|
+$780K
|
+4,356
|
+1%
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$48.6M
|
+$5.65M
|
+31,510
|
+11%
|
|
|
3
|
Eventide Asset Management
Boston,
Massachusetts
|
$40.3M
|
+$6.06M
|
+33,800
|
+14%
|
|
|
4
|
Suvretta Capital Management
New York
|
$36.3M
|
+$3.66M
|
+20,410
|
+9%
|
|
|
5
|
First Light Asset Management
Edina,
Minnesota
|
$33.4M
|
+$988K
|
+5,515
|
+3%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$31.5M
|
+$49.8K
|
+278
|
+0.1%
|
|
|
7
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
$27.6M
|
+$1.08M
|
+6,031
|
+3%
|
|
|
8
|
SV Health Investors
Boston,
Massachusetts
|
$27.1M
|
–
|
–
|
–
|
|
|
9
|
Frazier Management
Seattle,
Washington
|
$26.4M
|
+$5.51M
|
+30,782
|
+21%
|
|
|
10
|
Samsara BioCapital
Palo Alto,
California
|
$24.9M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$23.7M
|
-$2M
|
-11,151
|
-7%
|
|
|
12
|
Holocene Advisors
New York
|
$23.6M
|
-$428K
|
-2,389
|
-1%
|
|
|
13
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$16.6M
|
-$8.13M
|
-45,397
|
-29%
|
|
|
14
|
BVF Inc
San Francisco,
California
|
$13.8M
|
+$1.76M
|
+9,832
|
+12%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$11.1M
|
+$926K
|
+5,170
|
+7%
|
|
|
16
|
Fidelity Investments
Boston,
Massachusetts
|
$11M
|
–
|
–
|
–
|
|
|
17
|
Opaleye Management
Boston,
Massachusetts
|
$10.1M
|
+$2.55M
|
+14,220
|
+26%
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$8.88M
|
-$1.31M
|
-7,287
|
-11%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$8.11M
|
+$165K
|
+920
|
+2%
|
|
|
20
|
Lombard Odier Asset Management (Switzerland)
Petit-Lancy,
Switzerland
|
$7.86M
|
+$800K
|
+4,468
|
+9%
|
|
|
21
|
|
$5.4M
|
+$652K
|
+3,639
|
+11%
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
$5.37M
|
+$1.97M
|
+10,969
|
+44%
|
|
|
23
|
Barclays
London,
United Kingdom
|
$5.27M
|
+$426K
|
+2,377
|
+7%
|
|
|
24
|
Tekla Capital Management
Boston,
Massachusetts
|
$4.88M
|
-$1.3M
|
-7,230
|
-18%
|
|
|
25
|
Sphera Funds Management
Tel Aviv,
Israel
|
$4.19M
|
-$235K
|
-1,313
|
-4%
|
|
