|
1
|
|
55,1 Mio. $
|
+780.377 $
|
+4.356
|
+1 %
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
48,6 Mio. $
|
+5,65 Mio. $
|
+31.510
|
+11 %
|
|
|
3
|
Eventide Asset Management
Boston,
Massachusetts
|
40,3 Mio. $
|
+6,06 Mio. $
|
+33.800
|
+14 %
|
|
|
4
|
Suvretta Capital Management
New York
|
36,3 Mio. $
|
+3,66 Mio. $
|
+20.410
|
+9 %
|
|
|
5
|
First Light Asset Management
Edina,
Minnesota
|
33,4 Mio. $
|
+988.012 $
|
+5.515
|
+3 %
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
31,5 Mio. $
|
+49.804 $
|
+278
|
+0,1 %
|
|
|
7
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
27,6 Mio. $
|
+1,08 Mio. $
|
+6.031
|
+3 %
|
|
|
8
|
SV Health Investors
Boston,
Massachusetts
|
27,1 Mio. $
|
–
|
–
|
–
|
|
|
9
|
Frazier Management
Seattle,
Washington
|
26,4 Mio. $
|
+5,51 Mio. $
|
+30.782
|
+21 %
|
|
|
10
|
Samsara BioCapital
Palo Alto,
California
|
24,9 Mio. $
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
23,7 Mio. $
|
-2 Mio. $
|
-11.151
|
-7 %
|
|
|
12
|
Holocene Advisors
New York
|
23,6 Mio. $
|
-427.989 $
|
-2.389
|
-1 %
|
|
|
13
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
16,6 Mio. $
|
-8,13 Mio. $
|
-45.397
|
-29 %
|
|
|
14
|
BVF Inc
San Francisco,
California
|
13,8 Mio. $
|
+1,76 Mio. $
|
+9.832
|
+12 %
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
11,1 Mio. $
|
+926.206 $
|
+5.170
|
+7 %
|
|
|
16
|
Fidelity Investments
Boston,
Massachusetts
|
11 Mio. $
|
–
|
–
|
–
|
|
|
17
|
Opaleye Management
Boston,
Massachusetts
|
10,1 Mio. $
|
+2,55 Mio. $
|
+14.220
|
+26 %
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
8,88 Mio. $
|
-1,31 Mio. $
|
-7.287
|
-11 %
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
8,11 Mio. $
|
+164.818 $
|
+920
|
+2 %
|
|
|
20
|
Lombard Odier Asset Management (Switzerland)
Petit-Lancy,
Switzerland
|
7,86 Mio. $
|
+800.442 $
|
+4.468
|
+9 %
|
|
|
21
|
|
5,4 Mio. $
|
+651.927 $
|
+3.639
|
+11 %
|
|
|
22
|
Dimensional Fund Advisors
Austin,
Texas
|
5,37 Mio. $
|
+1,97 Mio. $
|
+10.969
|
+44 %
|
|
|
23
|
Barclays
London,
United Kingdom
|
5,27 Mio. $
|
+425.840 $
|
+2.377
|
+7 %
|
|
|
24
|
Tekla Capital Management
Boston,
Massachusetts
|
4,88 Mio. $
|
-1,3 Mio. $
|
-7.230
|
-18 %
|
|
|
25
|
Sphera Funds Management
Tel Aviv,
Israel
|
4,19 Mio. $
|
-235.224 $
|
-1.313
|
-4 %
|
|
