|
1
|
|
$59M
|
+$11.1M
|
+67,037
|
+33%
|
|
|
2
|
Eventide Asset Management
Boston,
Massachusetts
|
$51.5M
|
+$6.37M
|
+38,500
|
+19%
|
|
|
3
|
Franklin Resources
San Mateo,
California
|
$48.3M
|
+$36.9M
|
+222,692
|
New
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$46M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$41.8M
|
+$10.3M
|
+62,381
|
+48%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$40.3M
|
-$20.4M
|
-123,304
|
-40%
|
|
|
7
|
SV Health Investors
Boston,
Massachusetts
|
$39.6M
|
–
|
–
|
–
|
|
|
8
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
$36.8M
|
–
|
–
|
–
|
|
|
9
|
Samsara BioCapital
Palo Alto,
California
|
$36.4M
|
–
|
–
|
–
|
|
|
10
|
Point72 Asset Management
Stamford,
Connecticut
|
$30.6M
|
+$6.6M
|
+39,881
|
+39%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$28.1M
|
+$1.21M
|
+7,287
|
+6%
|
|
|
12
|
Holocene Advisors
New York
|
$23.2M
|
+$17.7M
|
+106,726
|
New
|
|
|
13
|
Suvretta Capital Management
New York
|
$22.5M
|
-$2.23M
|
-13,476
|
-12%
|
|
|
14
|
Frazier Management
Seattle,
Washington
|
$21.7M
|
+$16.6M
|
+100,142
|
New
|
|
|
15
|
First Light Asset Management
Edina,
Minnesota
|
$18M
|
+$13.7M
|
+82,710
|
New
|
|
|
16
|
Fidelity International
Hamilton,
Bermuda
|
$16.2M
|
+$6.48M
|
+39,156
|
+111%
|
|
|
17
|
Tekla Capital Management
Boston,
Massachusetts
|
$15.3M
|
+$1.01M
|
+6,125
|
+10%
|
|
|
18
|
Avidity Partners Management
Dallas,
Texas
|
$13.6M
|
+$10.4M
|
+62,600
|
New
|
|
|
19
|
Ikarian Capital
Dallas,
Texas
|
$13.4M
|
+$2.11M
|
+12,736
|
+26%
|
|
|
20
|
Fidelity Investments
Boston,
Massachusetts
|
$11.8M
|
+$3.38M
|
+20,440
|
+60%
|
|
|
21
|
Adage Capital Partners
Boston,
Massachusetts
|
$10.3M
|
-$4.14M
|
-25,000
|
-34%
|
|
|
22
|
State Street
Boston,
Massachusetts
|
$9.83M
|
+$2.13M
|
+12,877
|
+40%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$9.09M
|
+$1.62M
|
+9,804
|
+31%
|
|
|
24
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$7.99M
|
+$6.09M
|
+36,811
|
New
|
|
|
25
|
Marshall Wace North America
New York
|
$7.77M
|
+$5.93M
|
+35,799
|
New
|
|
