|
1
|
|
$70.6M
|
+$9.11M
|
+38,404
|
+14%
|
|
|
2
|
Franklin Resources
San Mateo,
California
|
$60.2M
|
+$10M
|
+41,988
|
+19%
|
|
|
3
|
State Street
Boston,
Massachusetts
|
$57.2M
|
+$48.9M
|
+206,139
|
+455%
|
|
|
4
|
Eventide Asset Management
Boston,
Massachusetts
|
$54M
|
–
|
–
|
–
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$48.2M
|
–
|
–
|
–
|
|
|
6
|
First Light Asset Management
Edina,
Minnesota
|
$46.8M
|
+$29.2M
|
+123,135
|
+149%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$46.4M
|
+$2.76M
|
+11,637
|
+6%
|
|
|
8
|
SV Health Investors
Boston,
Massachusetts
|
$41.5M
|
–
|
–
|
–
|
|
|
9
|
Baillie Gifford & Co
Edinburgh,
United Kingdom
|
$38.6M
|
–
|
–
|
–
|
|
|
10
|
Samsara BioCapital
Palo Alto,
California
|
$38.1M
|
–
|
–
|
–
|
|
|
11
|
Holocene Advisors
New York
|
$32.4M
|
+$8.45M
|
+35,595
|
+33%
|
|
|
12
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$30.8M
|
+$32.2M
|
+135,499
|
New
|
|
|
13
|
Suvretta Capital Management
New York
|
$29.2M
|
+$5.92M
|
+24,957
|
+24%
|
|
|
14
|
Frazier Management
Seattle,
Washington
|
$22.8M
|
–
|
–
|
–
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$22.2M
|
-$7.51M
|
-31,638
|
-24%
|
|
|
16
|
Point72 Asset Management
Stamford,
Connecticut
|
$21.8M
|
-$10.7M
|
-45,111
|
-32%
|
|
|
17
|
BVF Inc
San Francisco,
California
|
$18.8M
|
-$24.4M
|
-102,733
|
-55%
|
|
|
18
|
|
$17.6M
|
+$15.2M
|
+64,149
|
+487%
|
|
|
19
|
Fidelity International
Hamilton,
Bermuda
|
$17.6M
|
+$652K
|
+2,749
|
+4%
|
|
|
20
|
Fidelity Investments
Boston,
Massachusetts
|
$16.8M
|
+$4.61M
|
+19,430
|
+36%
|
|
|
21
|
Tekla Capital Management
Boston,
Massachusetts
|
$13.1M
|
-$3.05M
|
-12,870
|
-18%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$12.9M
|
+$3.51M
|
+14,813
|
+35%
|
|
|
23
|
Millennium Management
New York
|
$12.7M
|
+$6.82M
|
+28,732
|
+107%
|
|
|
24
|
Verition Fund Management
Greenwich,
Connecticut
|
$10.7M
|
+$3.45M
|
+14,556
|
+45%
|
|
|
25
|
Adage Capital Partners
Boston,
Massachusetts
|
$10.2M
|
-$586K
|
-2,470
|
-5%
|
|
