|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$848M
|
+$83.5M
|
+1,862,477
|
+12%
|
|
|
2
|
Siren LLC
Greenwich,
Connecticut
|
$532M
|
–
|
–
|
–
|
|
|
3
|
Redmile Group
San Francisco,
California
|
$446M
|
+$172M
|
+3,845,775
|
+74%
|
|
|
4
|
|
$367M
|
+$11.3M
|
+252,259
|
+3%
|
|
|
5
|
Samsara BioCapital
Palo Alto,
California
|
$339M
|
–
|
–
|
–
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$330M
|
+$42.9M
|
+958,227
|
+17%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$305M
|
-$8.77M
|
-195,819
|
-3%
|
|
|
8
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$205M
|
+$33.7M
|
+751,054
|
+22%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$198M
|
-$140K
|
-3,117
|
-0.1%
|
|
|
10
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$191M
|
+$174M
|
+3,891,347
|
New
|
|
|
11
|
Bellevue Group
Kuesnacht,
Switzerland
|
$176M
|
-$21.2M
|
-472,019
|
-12%
|
|
|
12
|
Jennison Associates
New York
|
$164M
|
+$24.4M
|
+545,304
|
+20%
|
|
|
13
|
Janus Henderson Group
London,
|
$110M
|
+$20.7M
|
+462,669
|
+26%
|
|
|
14
|
Eventide Asset Management
Boston,
Massachusetts
|
$108M
|
-$10.5M
|
-233,948
|
-10%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$106M
|
+$5.15M
|
+115,012
|
+6%
|
|
|
16
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$101M
|
+$1.03M
|
+22,921
|
+1%
|
|
|
17
|
Polar Capital Holdings
London,
United Kingdom
|
$97.5M
|
+$29.6M
|
+661,617
|
+50%
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
$94.4M
|
-$1.46M
|
-32,644
|
-2%
|
|
|
19
|
Holocene Advisors
New York
|
$93M
|
+$22.6M
|
+503,807
|
+36%
|
|
|
20
|
Woodline Partners
San Francisco,
California
|
$73.8M
|
+$13M
|
+289,382
|
+24%
|
|
|
21
|
|
$68.8M
|
+$3.35M
|
+74,770
|
+6%
|
|
|
22
|
Bank of America
Charlotte,
North Carolina
|
$65.7M
|
+$12.8M
|
+286,126
|
+27%
|
|
|
23
|
Vestal Point Capital
New York
|
$65.1M
|
+$28M
|
+624,422
|
+89%
|
|
|
24
|
Paradigm Biocapital Advisors
New York
|
$60.3M
|
-$82.3M
|
-1,836,077
|
-60%
|
|
|
25
|
Capital World Investors
Los Angeles,
California
|
$55.5M
|
–
|
–
|
–
|
|
