|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$522M
|
+$6.2M
|
+177,203
|
+1%
|
|
|
2
|
Siren LLC
Greenwich,
Connecticut
|
$344M
|
–
|
–
|
–
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$256M
|
-$65.7M
|
-1,878,592
|
-21%
|
|
|
4
|
|
$252M
|
+$2.25M
|
+64,307
|
+1%
|
|
|
5
|
Samsara BioCapital
Palo Alto,
California
|
$209M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$183M
|
+$1.87M
|
+53,333
|
+1%
|
|
|
7
|
Wellington Management Group
Boston,
Massachusetts
|
$169M
|
+$88.2M
|
+2,521,022
|
+125%
|
|
|
8
|
Redmile Group
San Francisco,
California
|
$145M
|
-$860K
|
-24,583
|
-0.6%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$140M
|
+$24.1M
|
+688,807
|
+22%
|
|
|
10
|
Bellevue Group
Kuesnacht,
Switzerland
|
$121M
|
+$10.4M
|
+297,242
|
+10%
|
|
|
11
|
Janus Henderson Group
London,
|
$112M
|
+$19.7M
|
+563,159
|
+23%
|
|
|
12
|
Eventide Asset Management
Boston,
Massachusetts
|
$104M
|
-$3.98M
|
-113,790
|
-4%
|
|
|
13
|
Holocene Advisors
New York
|
$91.7M
|
+$86.1M
|
+2,461,596
|
New
|
|
|
14
|
Driehaus Capital Management
Chicago,
Illinois
|
$75.4M
|
+$29.6M
|
+846,444
|
+72%
|
|
|
15
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$75M
|
+$1.38M
|
+39,429
|
+2%
|
|
|
16
|
Paradigm Biocapital Advisors
New York
|
$74.8M
|
+$14.3M
|
+409,191
|
+26%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$72.8M
|
+$2.36M
|
+67,400
|
+4%
|
|
|
18
|
Adage Capital Partners
Boston,
Massachusetts
|
$72.7M
|
+$25.8M
|
+736,866
|
+61%
|
|
|
19
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$67.9M
|
–
|
–
|
–
|
|
|
20
|
Jennison Associates
New York
|
$59.8M
|
+$43.4M
|
+1,240,566
|
+339%
|
|
|
21
|
|
$58.2M
|
+$9.55M
|
+273,116
|
+21%
|
|
|
22
|
Vestal Point Capital
New York
|
$55.9M
|
–
|
–
|
–
|
|
|
23
|
Pictet Asset Management
Carouge,
Switzerland
|
$49.3M
|
+$11.7M
|
+335,467
|
+34%
|
|
|
24
|
RA Capital Management
Boston,
Massachusetts
|
$43.5M
|
+$1.06M
|
+30,335
|
+3%
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$42.1M
|
+$27.7M
|
+792,760
|
+234%
|
|
