|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$678M
|
+$51.3M
|
+1,368,597
|
+10%
|
|
|
2
|
Siren LLC
Greenwich,
Connecticut
|
$477M
|
+$59.1M
|
+1,575,008
|
+17%
|
|
|
3
|
|
$318M
|
+$17.1M
|
+456,847
|
+7%
|
|
|
4
|
Samsara BioCapital
Palo Alto,
California
|
$304M
|
+$48.2M
|
+1,284,756
|
+23%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$282M
|
-$18M
|
-480,621
|
-7%
|
|
|
6
|
Wellington Management Group
Boston,
Massachusetts
|
$254M
|
+$45.5M
|
+1,213,541
|
+27%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$230M
|
+$49.4M
|
+1,316,390
|
+34%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$229M
|
+$10.5M
|
+280,538
|
+6%
|
|
|
9
|
Bellevue Group
Kuesnacht,
Switzerland
|
$179M
|
+$30.5M
|
+812,055
|
+25%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$178M
|
+$10.2M
|
+271,331
|
+7%
|
|
|
11
|
Orbis Allan Gray
Hamilton,
Bermuda
|
$151M
|
+$117M
|
+3,126,677
|
+1,034%
|
|
|
12
|
Paradigm Biocapital Advisors
New York
|
$135M
|
+$39.5M
|
+1,052,412
|
+52%
|
|
|
13
|
Jennison Associates
New York
|
$123M
|
+$44.6M
|
+1,188,676
|
+74%
|
|
|
14
|
Eventide Asset Management
Boston,
Massachusetts
|
$107M
|
-$13.8M
|
-368,123
|
-13%
|
|
|
15
|
|
$91.6M
|
+$78M
|
+2,079,515
|
New
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$89.6M
|
+$2.97M
|
+79,214
|
+4%
|
|
|
17
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$89.3M
|
+$464K
|
+12,365
|
+0.6%
|
|
|
18
|
Driehaus Capital Management
Chicago,
Illinois
|
$86M
|
-$2.67M
|
-71,082
|
-4%
|
|
|
19
|
Janus Henderson Group
London,
|
$78.2M
|
-$46.5M
|
-1,239,277
|
-41%
|
|
|
20
|
Holocene Advisors
New York
|
$61.1M
|
-$40.3M
|
-1,074,476
|
-44%
|
|
|
21
|
|
$58.3M
|
-$8.96M
|
-238,876
|
-15%
|
|
|
22
|
Polar Capital Holdings
London,
United Kingdom
|
$58.2M
|
+$19.8M
|
+527,929
|
+66%
|
|
|
23
|
Woodline Partners
San Francisco,
California
|
$53.3M
|
+$12.8M
|
+340,038
|
+39%
|
|
|
24
|
Pictet Asset Management
Carouge,
Switzerland
|
$52.7M
|
-$4.76M
|
-126,964
|
-10%
|
|
|
25
|
Capital World Investors
Los Angeles,
California
|
$49.7M
|
–
|
–
|
–
|
|
