|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$443M
|
+$6.13M
|
+159,229
|
+1%
|
|
|
2
|
Siren LLC
Greenwich,
Connecticut
|
$297M
|
–
|
–
|
–
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$286M
|
-$15M
|
-389,535
|
-4%
|
|
|
4
|
|
$235M
|
+$5.19M
|
+134,899
|
+2%
|
|
|
5
|
Samsara BioCapital
Palo Alto,
California
|
$180M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$156M
|
+$3.91M
|
+101,723
|
+2%
|
|
|
7
|
Redmile Group
San Francisco,
California
|
$141M
|
-$5.83M
|
-151,600
|
-3%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$101M
|
+$19M
|
+494,845
|
+19%
|
|
|
9
|
Eventide Asset Management
Boston,
Massachusetts
|
$85.6M
|
+$91.1K
|
+2,368
|
+0.1%
|
|
|
10
|
Polar Capital Holdings
London,
United Kingdom
|
$83.1M
|
-$4.81M
|
-125,000
|
-5%
|
|
|
11
|
Bellevue Group
Kuesnacht,
Switzerland
|
$80.6M
|
-$146K
|
-3,800
|
-0.2%
|
|
|
12
|
Adage Capital Partners
Boston,
Massachusetts
|
$64.9M
|
+$16.3M
|
+423,131
|
+27%
|
|
|
13
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$62.5M
|
+$1.75M
|
+45,517
|
+2%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$59.4M
|
+$2.97M
|
+77,125
|
+4%
|
|
|
15
|
Wellington Management Group
Boston,
Massachusetts
|
$59.3M
|
+$4.59M
|
+119,375
|
+7%
|
|
|
16
|
Commodore Capital
New York
|
$56.1M
|
+$30.6M
|
+795,000
|
+84%
|
|
|
17
|
Janus Henderson Group
London,
|
$54.8M
|
+$31.6M
|
+821,009
|
+97%
|
|
|
18
|
Marshall Wace
London,
United Kingdom
|
$52.6M
|
-$50.4M
|
-1,310,108
|
-44%
|
|
|
19
|
|
$52.5M
|
-$13.7M
|
-357,397
|
-18%
|
|
|
20
|
|
$45.2M
|
-$12.2M
|
-316,159
|
-18%
|
|
|
21
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$44.2M
|
-$22.7M
|
-588,922
|
-30%
|
|
|
22
|
Vestal Point Capital
New York
|
$41.8M
|
+$50M
|
+1,300,000
|
New
|
|
|
23
|
RA Capital Management
Boston,
Massachusetts
|
$36.5M
|
+$43M
|
+1,118,837
|
+6,351%
|
|
|
24
|
Capital World Investors
Los Angeles,
California
|
$36.3M
|
+$15.7M
|
+406,795
|
+56%
|
|
|
25
|
Man Group
London,
United Kingdom
|
$31.8M
|
+$38M
|
+987,710
|
New
|
|
