|
1
|
Vivo Capital
Palo Alto,
California
|
$318M
|
-$49.1M
|
-1,025,000
|
-14%
|
|
|
2
|
Janus Henderson Group
London,
|
$206M
|
+$34.6M
|
+722,226
|
+22%
|
|
|
3
|
Carlyle Group
Washington,
District of Columbia
|
$205M
|
–
|
–
|
–
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$168M
|
+$22.4M
|
+468,052
|
+16%
|
|
|
5
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$165M
|
+$9.02M
|
+188,341
|
+6%
|
|
|
6
|
Perceptive Advisors
New York
|
$162M
|
–
|
–
|
–
|
|
|
7
|
Avoro Capital Advisors
New York
|
$110M
|
+$4.28M
|
+89,334
|
+4%
|
|
|
8
|
|
$102M
|
+$7.1M
|
+148,363
|
+8%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$79.8M
|
+$3.73M
|
+77,974
|
+5%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$66.1M
|
+$39.8M
|
+831,643
|
+174%
|
|
|
11
|
Commodore Capital
New York
|
$63.6M
|
-$7.9M
|
-165,000
|
-12%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$57.7M
|
+$6.8M
|
+142,033
|
+14%
|
|
|
13
|
Alyeska Investment Group
Chicago,
Illinois
|
$49.3M
|
+$46.7M
|
+976,105
|
New
|
|
|
14
|
Frazier Life Sciences Management
Palo Alto,
California
|
$44.2M
|
–
|
–
|
–
|
|
|
15
|
Vestal Point Capital
New York
|
$36.4M
|
-$23M
|
-480,000
|
-40%
|
|
|
16
|
Wellington Management Group
Boston,
Massachusetts
|
$34.5M
|
+$13.9M
|
+290,135
|
+74%
|
|
|
17
|
Fidelity Investments
Boston,
Massachusetts
|
$33.6M
|
+$31.9M
|
+665,363
|
+6,048,755%
|
|
|
18
|
Holocene Advisors
New York
|
$30M
|
+$2.77M
|
+57,913
|
+11%
|
|
|
19
|
Sofinnova Investments
Menlo Park,
California
|
$29.6M
|
+$1.53M
|
+31,985
|
+6%
|
|
|
20
|
Pictet Asset Management
Carouge,
Switzerland
|
$29.1M
|
+$6.89M
|
+143,853
|
+33%
|
|
|
21
|
TCG Crossover Management
Palo Alto,
California
|
$27.8M
|
–
|
–
|
–
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$27.3M
|
+$2.45M
|
+51,189
|
+10%
|
|
|
23
|
|
$25.8M
|
+$515K
|
+10,763
|
+2%
|
|
|
24
|
Westfield Capital Management
Boston,
Massachusetts
|
$25M
|
+$23.7M
|
+495,708
|
New
|
|
|
25
|
Woodline Partners
San Francisco,
California
|
$20.3M
|
+$3.97M
|
+82,878
|
+26%
|
|
