|
1
|
Vivo Capital
Palo Alto,
California
|
$360M
|
–
|
–
|
–
|
|
|
2
|
Carlyle Group
Washington,
District of Columbia
|
$173M
|
+$54.9M
|
+1,213,758
|
+42%
|
|
|
3
|
Perceptive Advisors
New York
|
$132M
|
–
|
–
|
–
|
|
|
4
|
Janus Henderson Group
London,
|
$123M
|
+$15.7M
|
+346,914
|
+14%
|
|
|
5
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$103M
|
-$20.2M
|
-445,972
|
-16%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$83.2M
|
+$5.28M
|
+116,706
|
+6%
|
|
|
7
|
Avoro Capital Advisors
New York
|
$69.5M
|
+$38M
|
+840,000
|
+107%
|
|
|
8
|
Vestal Point Capital
New York
|
$53.5M
|
-$2.26M
|
-50,000
|
-4%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$41.5M
|
+$21.2M
|
+469,168
|
+94%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$41.5M
|
+$1.49K
|
+33
|
+0%
|
|
|
11
|
Frazier Life Sciences Management
Palo Alto,
California
|
$37.5M
|
+$18.6M
|
+410,730
|
+88%
|
|
|
12
|
Ikarian Capital
Dallas,
Texas
|
$24.2M
|
-$1.12M
|
-24,832
|
-4%
|
|
|
13
|
TCG Crossover Management
Palo Alto,
California
|
$23.5M
|
+$24.9M
|
+550,000
|
New
|
|
|
14
|
Wellington Management Group
Boston,
Massachusetts
|
$15.1M
|
+$6.37M
|
+140,875
|
+66%
|
|
|
15
|
Ally Bridge Group
New York
|
$14.4M
|
+$1.2M
|
+26,536
|
+9%
|
|
|
16
|
Pictet Asset Management
Carouge,
Switzerland
|
$14.3M
|
+$15.1M
|
+333,852
|
New
|
|
|
17
|
|
$14M
|
+$572K
|
+12,637
|
+4%
|
|
|
18
|
|
$13.7M
|
+$14.5M
|
+320,030
|
New
|
|
|
19
|
Emerald Advisers
Leola,
Pennsylvania
|
$12.9M
|
+$2.18M
|
+48,223
|
+19%
|
|
|
20
|
Emerald Mutual Fund Advisers Trust
Leola,
Pennsylvania
|
$9.92M
|
+$1.38M
|
+30,435
|
+15%
|
|
|
21
|
|
$9.37M
|
-$3.75M
|
-82,850
|
-27%
|
|
|
22
|
|
$9.07M
|
+$6.48M
|
+143,318
|
+209%
|
|
|
23
|
Ghost Tree Capital
New York
|
$8.56M
|
+$3.96M
|
+87,615
|
+78%
|
|
|
24
|
Marshall Wace
London,
United Kingdom
|
$7.54M
|
+$7.97M
|
+176,237
|
New
|
|
|
25
|
Commodore Capital
New York
|
$7.26M
|
-$24M
|
-530,467
|
-76%
|
|
