|
1
|
Vivo Capital
Palo Alto,
California
|
$299M
|
-$46.7M
|
-1,101,242
|
-13%
|
|
|
2
|
Carlyle Group
Washington,
District of Columbia
|
$166M
|
–
|
–
|
–
|
|
|
3
|
Janus Henderson Group
London,
|
$137M
|
+$20.7M
|
+488,062
|
+17%
|
|
|
4
|
Perceptive Advisors
New York
|
$131M
|
+$5.53M
|
+130,434
|
+4%
|
|
|
5
|
Nantahala Capital Management
New Canaan,
Connecticut
|
$126M
|
+$28.5M
|
+671,728
|
+28%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$116M
|
+$38.6M
|
+910,574
|
+47%
|
|
|
7
|
Avoro Capital Advisors
New York
|
$85.3M
|
+$19.8M
|
+466,666
|
+29%
|
|
|
8
|
|
$76M
|
+$65.1M
|
+1,537,156
|
+471%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$61.3M
|
+$22.6M
|
+533,098
|
+55%
|
|
|
10
|
Commodore Capital
New York
|
$58.1M
|
+$53.2M
|
+1,255,467
|
+741%
|
|
|
11
|
Vestal Point Capital
New York
|
$49M
|
-$2.12M
|
-50,000
|
-4%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$40.8M
|
+$1.25M
|
+29,566
|
+3%
|
|
|
13
|
Frazier Life Sciences Management
Palo Alto,
California
|
$35.7M
|
–
|
–
|
–
|
|
|
14
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$29.8M
|
+$30.9M
|
+729,841
|
New
|
|
|
15
|
Sofinnova Investments
Menlo Park,
California
|
$22.6M
|
+$17.1M
|
+403,584
|
+268%
|
|
|
16
|
TCG Crossover Management
Palo Alto,
California
|
$22.4M
|
–
|
–
|
–
|
|
|
17
|
Holocene Advisors
New York
|
$21.9M
|
+$22.7M
|
+536,451
|
New
|
|
|
18
|
|
$20.4M
|
+$12M
|
+282,122
|
+129%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$20M
|
+$13.6M
|
+322,086
|
+193%
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$19.5M
|
+$13.8M
|
+325,232
|
+213%
|
|
|
21
|
Millennium Management
New York
|
$18.7M
|
+$15.5M
|
+366,295
|
+397%
|
|
|
22
|
Ikarian Capital
Dallas,
Texas
|
$18.2M
|
-$5.08M
|
-119,960
|
-21%
|
|
|
23
|
Pictet Asset Management
Carouge,
Switzerland
|
$17.6M
|
+$4.15M
|
+97,908
|
+29%
|
|
|
24
|
Wellington Management Group
Boston,
Massachusetts
|
$16M
|
+$1.68M
|
+39,554
|
+11%
|
|
|
25
|
Woodline Partners
San Francisco,
California
|
$13M
|
+$9.02M
|
+212,745
|
+200%
|
|
