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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $3.42B invested in Rhythm Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 85 increasing their positions, 69 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
227
Holders Change
+24
Holders Change %
+11.82%
% of All Funds
3.08%
Holding in Top 10
7
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-36.36%
% of All Funds
0.1%
New
45
Increased
85
Reduced
69
Closed
20
Calls
$21.5M
Puts
$3.46M
Net Calls
+$18M
Net Calls Change
-$6.98M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$83.4M
2
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$71M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$23.9M
5
SL
Siren LLC
Connecticut
+$14.7M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$63.1M
2
PA
Perceptive Advisors
New York
-$60M
3
PCH
Polar Capital Holdings
United Kingdom
-$53M
4
Primecap Management
Primecap Management
California
-$41.5M
5
BBA
Baker Bros. Advisors
New York
-$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
X
176
Xponance
Pennsylvania
$231K +$10.4K +197 +5%
CCM
177
Cinctive Capital Management
New York
$231K -$4.15M -78,399 -95%
Mackenzie Financial
178
Mackenzie Financial
Ontario, Canada
$230K – – –
CPIG
179
Chicago Partners Investment Group
Illinois
$227K -$12K -186 -5%
LPL Financial
180
LPL Financial
California
$223K +$2.07K +39 +0.9%
SP
181
SIH Partners
Delaware
$211K +$211K +3,980 New
JGGDR
182
JGP Global Gestao de Recursos
Brazil
$203K -$82.3K -1,554 -29%
BC
183
Bayforest Capital
United Kingdom
$166K +$166K +3,134 New
Carson Wealth (CWM LLC)
184
Carson Wealth (CWM LLC)
Nebraska
$137K +$65.7K +1,240 +92%
KBC Group
185
KBC Group
Belgium
$119K – – –
Mirae Asset Global Investments
186
Mirae Asset Global Investments
South Korea
$116K +$3.73K +68 +3%
EWP
187
Elevation Wealth Partners
California
$104K – – –
AB
188
Amalgamated Bank
New York
$100K +$319 +6 +0.3%
WT
189
Whittier Trust
California
$93.2K – – –
GFM
190
GF Fund Management
China
$83.3K +$15K +283 +22%
Nisa Investment Advisors
191
Nisa Investment Advisors
Missouri
$65.7K -$2.38K -45 -4%
TRCT
192
Tower Research Capital (TRC)
New York
$56K -$184K -3,481 -77%
BAMF
193
BI Asset Management Fondsmaeglerselskab
Denmark
$34K +$34K +648 New
Osaic Holdings
194
Osaic Holdings
Arizona
$31.3K -$4.4K -83 -12%
AAP
195
Arax Advisory Partners
Colorado
$27.4K +$3.39K +64 +14%
SS
196
SBI Securities
Japan
$24.7K -$10.6K -200 -30%
AG
197
AmeriFlex Group
Nevada
$19.1K – – –
GI
198
GAMMA Investing
California
$14.9K +$4.24K +80 +40%
SAM
199
Smartleaf Asset Management
Massachusetts
$14K +$3.4K +62 +32%
Jones Financial Companies
200
Jones Financial Companies
Missouri
$12.7K – – –
6 7
8
9 10