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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $3.42B invested in Rhythm Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 85 increasing their positions, 69 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
227
Holders Change
+24
Holders Change %
+11.82%
% of All Funds
3.08%
Holding in Top 10
7
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-36.36%
% of All Funds
0.1%
New
45
Increased
85
Reduced
69
Closed
20
Calls
$21.5M
Puts
$3.46M
Net Calls
+$18M
Net Calls Change
-$6.98M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$83.4M
2
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$71M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$23.9M
5
SL
Siren LLC
Connecticut
+$14.7M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$63.1M
2
PA
Perceptive Advisors
New York
-$60M
3
PCH
Polar Capital Holdings
United Kingdom
-$53M
4
Primecap Management
Primecap Management
California
-$41.5M
5
BBA
Baker Bros. Advisors
New York
-$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
KK
151
KLP Kapitalforvaltning
Norway
$493K – – –
Zurich Cantonal Bank
152
Zurich Cantonal Bank
Switzerland
$473K -$5.72K -108 -1%
AIM
153
Aigen Investment Management
New York
$408K +$408K +7,701 New
PD
154
Point72 (DIFC)
United Arab Emirates
$352K +$352K +6,653 New
A
155
AlphaQuest
New York
$350K +$350K +6,606 +660,600%
VIA
156
Virtus Investment Advisers
Connecticut
$341K +$341K +6,446 New
BC
157
Bridgefront Capital
Texas
$340K +$95.9K +1,810 +39%
SFAM
158
Springhill Fund Asset Management
Hong Kong
$332K +$332K +6,277 New
Allianz Asset Management
159
Allianz Asset Management
Germany
$323K – – –
FCM
160
Fieldview Capital Management
Michigan
$320K +$320K +6,037 New
BC
161
BIT Capital
Germany
$319K +$319K +6,013 New
YIH
162
Y-Intercept (HK)
Hong Kong
$316K +$5.3K +100 +2%
JRP
163
Jasper Ridge Partners
California
$299K – – –
AIP
164
Ameritas Investment Partners
Nebraska
$294K – – –
ET
165
Entropy Technologies
New York
$291K +$291K +5,502 New
Public Employees Retirement Association of Colorado
166
Public Employees Retirement Association of Colorado
Colorado
$289K – – –
EFM
167
E Fund Management
China
$286K +$286K +5,396 New
QC
168
Quadrature Capital
United Kingdom
$280K +$280K +5,278 New
GCP
169
GSA Capital Partners
United Kingdom
$269K +$269K +5,069 New
GAM
170
Gotham Asset Management
New York
$252K -$108K -2,036 -30%
Prudential Financial
171
Prudential Financial
New Jersey
$243K +$11.2K +200 +5%
AWM
172
Avior Wealth Management
Nebraska
$243K +$243K +4,589 New
Mariner
173
Mariner
Kansas
$243K +$3.18K +60 +1%
PNC Financial Services Group
174
PNC Financial Services Group
Pennsylvania
$239K +$223K +4,214 +1,386%
Verition Fund Management
175
Verition Fund Management
Connecticut
$234K -$191K -3,613 -45%
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