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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $3.42B invested in Rhythm Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 85 increasing their positions, 69 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
227
Holders Change
+24
Holders Change %
+11.82%
% of All Funds
3.08%
Holding in Top 10
7
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-36.36%
% of All Funds
0.1%
New
45
Increased
85
Reduced
69
Closed
20
Calls
$21.5M
Puts
$3.46M
Net Calls
+$18M
Net Calls Change
-$6.98M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$83.4M
2
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$71M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$23.9M
5
SL
Siren LLC
Connecticut
+$14.7M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$63.1M
2
PA
Perceptive Advisors
New York
-$60M
3
PCH
Polar Capital Holdings
United Kingdom
-$53M
4
Primecap Management
Primecap Management
California
-$41.5M
5
BBA
Baker Bros. Advisors
New York
-$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
Handelsbanken Fonder
126
Handelsbanken Fonder
Sweden
$902K – – –
New York State Common Retirement Fund
127
New York State Common Retirement Fund
New York
$893K – – –
LWL
128
Leo Wealth LLC
Texas
$848K +$848K +16,000 New
BG
129
Bellevue Group
Switzerland
$824K -$426K -8,046 -34%
HSBC Holdings
130
HSBC Holdings
United Kingdom
$823K -$37.9K -717 -4%
FT
131
Fiduciary Trust
Massachusetts
$795K -$265K -5,000 -25%
AI
132
Atom Investors
Texas
$793K +$178K +3,357 +29%
ProShare Advisors
133
ProShare Advisors
Maryland
$779K -$192K -3,624 -20%
State Board of Administration of Florida Retirement System
134
State Board of Administration of Florida Retirement System
Florida
$777K – – –
Renaissance Technologies
135
Renaissance Technologies
New York
$748K +$748K +14,112 New
VCM
136
Voleon Capital Management
California
$732K +$732K +13,819 New
American Century Companies
137
American Century Companies
Missouri
$704K -$1.09M -20,484 -61%
ASRS
138
Arizona State Retirement System
Arizona
$698K -$5.62K -106 -0.8%
CUAMC
139
China Universal Asset Management Company
China
$672K -$18.5K -349 -3%
PA
140
Profund Advisors
Maryland
$659K +$104K +1,963 +19%
Teacher Retirement System of Texas
141
Teacher Retirement System of Texas
Texas
$657K -$62.6K -1,182 -9%
Creative Planning
142
Creative Planning
Kansas
$653K +$112K +2,109 +21%
CWM
143
CIBC World Markets
New York
$643K +$372K +7,025 +137%
Two Sigma Advisers
144
Two Sigma Advisers
New York
$641K -$53K -1,000 -8%
ETC
145
Exchange Traded Concepts
Oklahoma
$631K -$24.5K -463 -4%
PFSRSONJ
146
Police & Firemen's Retirement System of New Jersey
New Jersey
$617K – – –
Canada Life
147
Canada Life
Manitoba, Canada
$615K – – –
PAP
148
Persistent Asset Partners
Hong Kong
$609K -$361K -6,811 -37%
AAM
149
Advisors Asset Management
Colorado
$543K +$168K +3,176 +45%
CFS
150
Cannon Financial Strategists
Georgia
$530K – – –
4 5
6
7 8