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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $3.42B invested in Rhythm Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 85 increasing their positions, 69 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
227
Holders Change
+24
Holders Change %
+11.82%
% of All Funds
3.08%
Holding in Top 10
7
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-36.36%
% of All Funds
0.1%
New
45
Increased
85
Reduced
69
Closed
20
Calls
$21.5M
Puts
$3.46M
Net Calls
+$18M
Net Calls Change
-$6.98M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$83.4M
2
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$71M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$23.9M
5
SL
Siren LLC
Connecticut
+$14.7M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$63.1M
2
PA
Perceptive Advisors
New York
-$60M
3
PCH
Polar Capital Holdings
United Kingdom
-$53M
4
Primecap Management
Primecap Management
California
-$41.5M
5
BBA
Baker Bros. Advisors
New York
-$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
AllianceBernstein
76
AllianceBernstein
Tennessee
$3.26M – – –
AG
77
Algert Global
California
$3.26M +$1.05M +19,910 +48%
Rafferty Asset Management
78
Rafferty Asset Management
New York
$3.06M +$389K +7,338 +15%
SSA
79
Schonfeld Strategic Advisors
New York
$3.03M -$135K -2,550 -4%
KCM
80
Kennedy Capital Management
Missouri
$2.91M +$2.91M +54,930 New
Legal & General Group
81
Legal & General Group
United Kingdom
$2.71M -$34.2K -645 -1%
Connor, Clark & Lunn Investment Management (CC&L)
82
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$2.68M +$2.36M +44,468 +730%
TD Asset Management
83
TD Asset Management
Ontario, Canada
$2.66M +$127K +2,400 +5%
DP
84
Diadema Partners
New Jersey
$2.65M -$1.32M -25,000 -33%
AGP
85
Artia Global Partners
Florida
$2.65M – – –
NFGH
86
Nan Fung Group Holdings
Hong Kong
$2.6M – – –
AA
87
ALPS Advisors
Colorado
$2.45M -$185K -3,493 -7%
EI
88
EAM Investors
California
$2.39M -$952K -17,970 -28%
Deutsche Bank
89
Deutsche Bank
Germany
$2.32M -$263K -4,966 -10%
California State Teachers Retirement System (CalSTRS)
90
California State Teachers Retirement System (CalSTRS)
California
$2.26M -$43K -812 -2%
JF
91
Jump Financial
Illinois
$2.21M +$2.21M +41,760 New
ACM
92
Aquatic Capital Management
Illinois
$2.2M +$1.71M +32,253 +350%
AQR Capital Management
93
AQR Capital Management
Connecticut
$2.09M +$1.25M +23,506 +148%
TI
94
Trexquant Investment
Connecticut
$2.05M +$1.64M +30,926 +397%
Principal Financial Group
95
Principal Financial Group
Iowa
$1.97M +$14.4K +272 +0.7%
WCM
96
Wedge Capital Management
North Carolina
$1.96M -$605K -11,427 -24%
ACM
97
ADAR1 Capital Management
Texas
$1.95M +$315K +5,949 +19%
Walleye Capital
98
Walleye Capital
New York
$1.9M -$5.75M -108,514 -75%
State of New Jersey Common Pension Fund D
99
State of New Jersey Common Pension Fund D
New Jersey
$1.87M +$20.6K +388 +1%
Mirae Asset Global ETFs Holdings
100
Mirae Asset Global ETFs Holdings
Hong Kong
$1.87M +$113K +2,126 +6%
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4
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