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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $3.42B invested in Rhythm Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 85 increasing their positions, 69 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
227
Holders Change
+24
Holders Change %
+11.82%
% of All Funds
3.08%
Holding in Top 10
7
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-36.36%
% of All Funds
0.1%
New
45
Increased
85
Reduced
69
Closed
20
Calls
$21.5M
Puts
$3.46M
Net Calls
+$18M
Net Calls Change
-$6.98M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$83.4M
2
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$71M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$23.9M
5
SL
Siren LLC
Connecticut
+$14.7M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$63.1M
2
PA
Perceptive Advisors
New York
-$60M
3
PCH
Polar Capital Holdings
United Kingdom
-$53M
4
Primecap Management
Primecap Management
California
-$41.5M
5
BBA
Baker Bros. Advisors
New York
-$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
UBS AM
51
UBS AM
Illinois
$6.66M -$4.91M -92,762 -42%
Russell Investments Group
52
Russell Investments Group
United Kingdom
$6.08M +$6.03M +113,781 +11,412%
Bank of America
53
Bank of America
North Carolina
$5.92M +$385K +7,264 +7%
Aberdeen Group
54
Aberdeen Group
United Kingdom
$5.73M +$1.46M +27,612 +34%
Lazard Asset Management
55
Lazard Asset Management
New York
$5.47M -$162K -3,059 -3%
PP
56
PDT Partners
New York
$5.41M +$3.1M +58,612 +134%
Barclays
57
Barclays
United Kingdom
$5.36M -$1.81M -34,180 -25%
Ameriprise
58
Ameriprise
Minnesota
$5.21M +$2.38M +44,914 +84%
Universal-Beteiligungs- und Servicegesellschaft
59
Universal-Beteiligungs- und Servicegesellschaft
Germany
$4.93M +$902K +17,021 +22%
Jane Street
60
Jane Street
New York
$4.83M +$1.73M +32,703 +56%
First Trust Advisors
61
First Trust Advisors
Illinois
$4.76M -$1.51M -28,558 -24%
HWAM
62
Hennion & Walsh Asset Management
New Jersey
$4.75M -$520K -9,825 -10%
Swiss National Bank
63
Swiss National Bank
Switzerland
$4.73M -$47.7K -900 -1%
Citigroup
64
Citigroup
New York
$4.57M +$870K +16,429 +24%
BNP Paribas Financial Markets
65
BNP Paribas Financial Markets
France
$4.56M +$43.3K +817 +1%
VOYA Investment Management
66
VOYA Investment Management
Georgia
$4.55M -$600K -11,320 -12%
RhumbLine Advisers
67
RhumbLine Advisers
Massachusetts
$4.54M +$158K +2,988 +4%
D.E. Shaw & Co
68
D.E. Shaw & Co
New York
$4.44M +$1.89M +35,671 +74%
Susquehanna International Group
69
Susquehanna International Group
Pennsylvania
$4.4M +$1.71M +32,316 +64%
HCA
70
Harbor Capital Advisors
Illinois
$4.09M +$2.49M +47,045 +156%
Wells Fargo
71
Wells Fargo
California
$3.74M +$1.76M +33,314 +89%
Citadel Advisors
72
Citadel Advisors
Florida
$3.71M +$1.57M +29,649 +73%
Neuberger Berman Group
73
Neuberger Berman Group
New York
$3.6M +$3.6M +67,939 New
Manulife (Manufacturers Life Insurance)
74
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.41M +$234K +4,417 +7%
Point72 Asset Management
75
Point72 Asset Management
Connecticut
$3.38M +$3.38M +63,842 New
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