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Rhythm Pharmaceuticals
RYTM

Overview Fund Activity

227 hedge funds and large institutions have $3.42B invested in Rhythm Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 85 increasing their positions, 69 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
227
Holders Change
+24
Holders Change %
+11.82%
% of All Funds
3.08%
Holding in Top 10
7
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-36.36%
% of All Funds
0.1%
New
45
Increased
85
Reduced
69
Closed
20
Calls
$21.5M
Puts
$3.46M
Net Calls
+$18M
Net Calls Change
-$6.98M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$83.4M
2
Westfield Capital Management
Westfield Capital Management
Massachusetts
+$71M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$27.2M
4
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$23.9M
5
SL
Siren LLC
Connecticut
+$14.7M

Top Sellers

1
FLSM
Frazier Life Sciences Management
California
-$63.1M
2
PA
Perceptive Advisors
New York
-$60M
3
PCH
Polar Capital Holdings
United Kingdom
-$53M
4
Primecap Management
Primecap Management
California
-$41.5M
5
BBA
Baker Bros. Advisors
New York
-$25.4M
Name Holding Trade Value Shares
Change 		Shares
Change %
BIG
226
Brooklyn Investment Group
New York
$265 +$265 +5 New
Norges Bank
227
Norges Bank
Norway
– -$11.5M -205,649 Closed
IHAM
228
Integral Health Asset Management
New York
– -$8.4M -150,000 Closed
EGI
229
EAM Global Investors
California
– -$3.19M -56,936 Closed
CM
230
Crestline Management
Texas
– -$1.4M -25,062 Closed
BPC
231
Bryce Point Capital
New York
– -$1.1M -19,607 Closed
CM
232
Castleark Management
Illinois
– -$1.03M -18,390 Closed
OAC
233
OMERS Administration Corp
Ontario, Canada
– -$425K -7,600 Closed
FC
234
Farringdon Capital
United Kingdom
– -$384K -6,854 Closed
JG
235
Jain Global
New York
– -$375K -6,700 Closed
VEA
236
Virtus ETF Advisers
New York
– -$352K -6,280 Closed
TTSTC
237
Texas Treasury Safekeeping Trust Company
Texas
– -$237K -4,230 Closed
Raymond James Financial
238
Raymond James Financial
Florida
– -$218K -3,892 Closed
FCH
239
Freestone Capital Holdings
Washington
– -$207K -3,700 Closed
Simplex Trading
240
Simplex Trading
Illinois
– -$138K -2,475 Closed
OWP
241
ORG Wealth Partners
Texas
– -$67.5K -1,206 Closed
SOW
242
State of Wyoming
Wyoming
– -$60.7K -1,084 Closed
N
243
Natixis
France
– -$55.8K -997 Closed
RS
244
R Squared
Hong Kong
– -$43.7K -780 Closed
RCM
245
Raleigh Capital Management
North Carolina
– -$28K -500 Closed
IA
246
IFP Advisors
Florida
– -$56 -1 Closed
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