We are live on ! Find out more
RLAY icon

Relay Therapeutics

199 hedge funds and large institutions have $867M invested in Relay Therapeutics in 2025 Q3 according to their latest regulatory filings, with 20 funds opening new positions, 63 increasing their positions, 63 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

2,019% more call options, than puts

Call options by funds: $3.98M | Put options by funds: $188K

47% more capital invested

Capital invested by funds: $592M → $867M (+$276M)

0% more funds holding in top 10

Funds holding in top 10: 55 (0)

0% more repeat investments, than reductions

Existing positions increased: 63 | Existing positions reduced: 63

3.34% less ownership

Funds ownership: 99.71%96.38% (-3.3%)

4% less funds holding

Funds holding: 208199 (-9)

23% less first-time investments, than exits

New positions opened: 20 | Existing positions closed: 26

Holders
199
Holders Change
-9
Holders Change %
-4.33%
% of All Funds
2.61%
Holding in Top 10
5
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.07%
New
20
Increased
63
Reduced
63
Closed
26
Calls
$3.98M
Puts
$188K
Net Calls
+$3.79M
Net Calls Change
+$3.92M
Name Holding Trade Value Shares
Change
Change in
Stake
SIAU
1
SB Investment Advisers (UK)
United Kingdom
$146M
CC
2
Commodore Capital
New York
$88.7M +$13.9M +3,650,000 +27%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$77.1M +$5.06M +1,327,972 +10%
BlackRock
4
BlackRock
New York
$71.8M -$744K -195,104 -1%
CC
5
Casdin Capital
New York
$59.2M -$218K -57,193 -0.5%
Vanguard Group
6
Vanguard Group
Pennsylvania
$49M +$60.6K +15,893 +0.2%
BG
7
Bellevue Group
Switzerland
$43.6M +$438K +114,740 +1%
TCM
8
Tang Capital Management
California
$42.1M
State Street
9
State Street
Massachusetts
$26.4M -$522K -136,801 -3%
NI
10
Nextech Invest
Switzerland
$20.1M
Geode Capital Management
11
Geode Capital Management
Massachusetts
$15.9M -$668K -175,080 -5%
KCM
12
Kynam Capital Management
New Jersey
$15.1M
Dimensional Fund Advisors
13
Dimensional Fund Advisors
Texas
$13M -$1.17M -306,510 -11%
MB
14
MPM BioImpact
Massachusetts
$11.9M
Goldman Sachs
15
Goldman Sachs
New York
$9.76M -$253K -66,296 -3%
TCM
16
TCG Crossover Management
California
$9.45M +$6.9M +1,810,351 New
Morgan Stanley
17
Morgan Stanley
New York
$9.21M +$1.3M +341,750 +24%
AI
18
Alphabet Inc
California
$8.19M
AQR Capital Management
19
AQR Capital Management
Connecticut
$6.79M +$830K +217,571 +20%
Bank of America
20
Bank of America
North Carolina
$6.24M -$474K -124,287 -9%
Balyasny Asset Management
21
Balyasny Asset Management
Illinois
$6.13M +$4.48M +1,174,971 New
Northern Trust
22
Northern Trust
Illinois
$6.08M +$12.7K +3,342 +0.3%
BBA
23
Baker Bros. Advisors
New York
$6.06M
T. Rowe Price Associates
24
T. Rowe Price Associates
Maryland
$5.94M -$6.63M -1,738,255 -60%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$5.87M -$59.1K -15,500 -1%

RLAY Hedge Fund Activity: Q3 2025 in Review

199 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q3 2025, worth a combined $867M — up 47% from $592M a quarter earlier.

Sellers outnumbered buyers: 26 funds closed out of RLAY and 20 opened new positions — a net loss of 6 holders — while 63 trimmed existing stakes and 63 added.

The largest buyer was Commodore Capital, adding an estimated $13.9M. The largest seller was JP Morgan Chase, cutting an estimated $14.8M.

  • 199 institutional investors held Relay Therapeutics (RLAY) as of Q3 2025, down from 208 in Q2 2025.
  • Funds reported $867M of Relay Therapeutics stock for Q3 2025, up 47% quarter-over-quarter.
  • 20 funds opened new Relay Therapeutics positions in Q3 2025 and 26 closed out, a net change of -6 holders.
  • The largest Relay Therapeutics buyer in Q3 2025 was Commodore Capital, an estimated $13.9M added.
  • The largest Relay Therapeutics seller in Q3 2025 was JP Morgan Chase, an estimated $14.8M sold.

Based on aggregated 13F filings for Q3 2025.