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Relay Therapeutics

207 hedge funds and large institutions have $439M invested in Relay Therapeutics in 2025 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 73 increasing their positions, 60 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

274% more call options, than puts

Call options by funds: $483K | Put options by funds: $129K

42% more first-time investments, than exits

New positions opened: 34 | Existing positions closed: 24

22% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 60

4% more funds holding

Funds holding: 199207 (+8)

0.73% more ownership

Funds ownership: 97.95%98.69% (+0.73%)

33% less funds holding in top 10

Funds holding in top 10: 64 (-2)

35% less capital invested

Capital invested by funds: $676M → $439M (-$237M)

Holders
207
Holders Change
+8
Holders Change %
+4.02%
% of All Funds
2.78%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
34
Increased
73
Reduced
60
Closed
24
Calls
$483K
Puts
$129K
Net Calls
+$354K
Net Calls Change
-$140K
Name Holding Trade Value Shares
Change
Change in
Stake
SIAU
1
SB Investment Advisers (UK)
United Kingdom
$73.1M
BlackRock
2
BlackRock
New York
$37.9M -$766K -195,464 -1%
Vanguard Group
3
Vanguard Group
Pennsylvania
$31.7M -$11.5M -2,924,789 -19%
Point72 Asset Management
4
Point72 Asset Management
Connecticut
$28.4M +$36.2M +9,234,314 +580%
CC
5
Casdin Capital
New York
$23.8M +$588K +150,000 +2%
TCM
6
Tang Capital Management
California
$21.1M
BG
7
Bellevue Group
Switzerland
$19.3M
State Street
8
State Street
Massachusetts
$13.5M -$472K -120,534 -2%
JP Morgan Chase
9
JP Morgan Chase
New York
$12.9M -$269K -68,672 -1%
Norges Bank
10
Norges Bank
Norway
$12.1M -$4.49M -1,146,741 -20%
NI
11
Nextech Invest
Switzerland
$10.1M
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$9.11M +$611K +156,050 +5%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$8.05M +$157K +39,961 +1%
KCM
14
Kynam Capital Management
New Jersey
$8.03M +$8.08M +2,063,292 +206%
Millennium Management
15
Millennium Management
New York
$7.71M +$1.47M +374,491 +15%
Dimensional Fund Advisors
16
Dimensional Fund Advisors
Texas
$7.33M -$650K -165,906 -6%
EAM
17
Eventide Asset Management
Massachusetts
$7.03M
MB
18
MPM BioImpact
Massachusetts
$6.02M +$106K +27,099 +1%
Renaissance Technologies
19
Renaissance Technologies
New York
$5.96M +$2.85M +726,920 +47%
FC
20
Finepoint Capital
Massachusetts
$5.55M -$227K -58,000 -3%
Goldman Sachs
21
Goldman Sachs
New York
$5.44M -$2.46M -627,974 -23%
Morgan Stanley
22
Morgan Stanley
New York
$4.17M +$1.15M +292,416 +22%
AI
23
Alphabet Inc
California
$4.11M
WP
24
Woodline Partners
California
$3.98M +$4.87M +1,241,657 +448%
BBA
25
Baker Bros. Advisors
New York
$3.04M

RLAY Hedge Fund Activity: Q1 2025 in Review

207 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q1 2025, worth a combined $439M — down 35% from $676M a quarter earlier.

Buyers outnumbered sellers: 34 funds opened new RLAY positions and 24 closed out — a net gain of 10 holders — while 73 added to existing stakes and 60 trimmed.

The largest buyer was Point72 Asset Management, adding an estimated $36.2M. The largest seller was Vanguard Group, cutting an estimated $11.5M.

  • 207 institutional investors held Relay Therapeutics (RLAY) as of Q1 2025, up from 199 in Q4 2024.
  • Funds reported $439M of Relay Therapeutics stock for Q1 2025, down 35% quarter-over-quarter.
  • 34 funds opened new Relay Therapeutics positions in Q1 2025 and 24 closed out, a net change of +10 holders.
  • The largest Relay Therapeutics buyer in Q1 2025 was Point72 Asset Management, an estimated $36.2M added.
  • The largest Relay Therapeutics seller in Q1 2025 was Vanguard Group, an estimated $11.5M sold.

Based on aggregated 13F filings for Q1 2025.