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Relay Therapeutics

208 hedge funds and large institutions have $592M invested in Relay Therapeutics in 2025 Q2 according to their latest regulatory filings, with 36 funds opening new positions, 73 increasing their positions, 55 reducing their positions, and 34 closing their positions.

New
Increased
Maintained
Reduced
Closed

35% more capital invested

Capital invested by funds: $439M → $592M (+$153M)

33% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 55

25% more funds holding in top 10

Funds holding in top 10: 45 (+1)

1.03% more ownership

Funds ownership: 98.69%99.71% (+1%)

6% more first-time investments, than exits

New positions opened: 36 | Existing positions closed: 34

0% more funds holding

Funds holding: 207208 (+1)

99% less call options, than puts

Call options by funds: $1K | Put options by funds: $128K

Holders
208
Holders Change
+1
Holders Change %
+0.48%
% of All Funds
2.74%
Holding in Top 10
5
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+25%
% of All Funds
0.07%
New
36
Increased
73
Reduced
55
Closed
34
Calls
$1K
Puts
$128K
Net Calls
-$127K
Net Calls Change
-$481K
Name Holding Trade Value Shares
Change
Change in
Stake
SIAU
1
SB Investment Advisers (UK)
United Kingdom
$96.6M
BlackRock
2
BlackRock
New York
$48.3M -$1.56M -524,312 -4%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$46.5M +$7.79M +2,618,637 +24%
CC
4
Commodore Capital
New York
$46.2M +$39.7M +13,350,000 New
CC
5
Casdin Capital
New York
$39.4M +$6.84M +2,300,000 +25%
Vanguard Group
6
Vanguard Group
Pennsylvania
$32.5M -$8.11M -2,725,569 -23%
BG
7
Bellevue Group
Switzerland
$28.5M +$2.54M +853,578 +12%
TCM
8
Tang Capital Management
California
$27.9M
State Street
9
State Street
Massachusetts
$18M +$130K +43,599 +0.8%
JP Morgan Chase
10
JP Morgan Chase
New York
$15M -$1.7M -571,368 -12%
NI
11
Nextech Invest
Switzerland
$13.3M
Geode Capital Management
12
Geode Capital Management
Massachusetts
$11.2M +$475K +159,548 +5%
KCM
13
Kynam Capital Management
New Jersey
$9.99M -$524K -176,278 -6%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$9.95M -$1.79M -601,855 -17%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$9.65M -$28.6K -9,631 -0.3%
MB
16
MPM BioImpact
Massachusetts
$7.9M -$39.4K -13,244 -0.6%
Goldman Sachs
17
Goldman Sachs
New York
$6.7M -$425K -142,828 -7%
Millennium Management
18
Millennium Management
New York
$6.47M -$3.19M -1,072,513 -36%
AI
19
Alphabet Inc
California
$5.43M
Renaissance Technologies
20
Renaissance Technologies
New York
$5.22M -$2.28M -767,900 -34%
Morgan Stanley
21
Morgan Stanley
New York
$4.92M -$508K -170,840 -11%
Bank of America
22
Bank of America
North Carolina
$4.57M +$2.28M +765,702 +138%
Northern Trust
23
Northern Trust
Illinois
$4.02M +$57K +19,164 +2%
BBA
24
Baker Bros. Advisors
New York
$4.01M
Two Sigma Advisers
25
Two Sigma Advisers
New York
$3.94M +$1.16M +388,600 +52%

RLAY Hedge Fund Activity: Q2 2025 in Review

208 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q2 2025, worth a combined $592M — up 35% from $439M a quarter earlier.

Buyers outnumbered sellers: 36 funds opened new RLAY positions and 34 closed out — a net gain of 2 holders — while 73 added to existing stakes and 55 trimmed.

The largest buyer was Commodore Capital, opening a new position worth an estimated $39.7M. The largest seller was Norges Bank, cutting an estimated $11.3M.

  • 208 institutional investors held Relay Therapeutics (RLAY) as of Q2 2025, up from 207 in Q1 2025.
  • Funds reported $592M of Relay Therapeutics stock for Q2 2025, up 35% quarter-over-quarter.
  • 36 funds opened new Relay Therapeutics positions in Q2 2025 and 34 closed out, a net change of +2 holders.
  • The largest Relay Therapeutics buyer in Q2 2025 was Commodore Capital, an estimated $39.7M added.
  • The largest Relay Therapeutics seller in Q2 2025 was Norges Bank, an estimated $11.3M sold.

Based on aggregated 13F filings for Q2 2025.