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Relay Therapeutics

242 hedge funds and large institutions have $1.83B invested in Relay Therapeutics in 2026 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 94 increasing their positions, 53 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,389% more call options, than puts

Call options by funds: $12.5M | Put options by funds: $842K

77% more repeat investments, than reductions

Existing positions increased: 94 | Existing positions reduced: 53

76% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 29

24% more capital invested

Capital invested by funds: $1.47B → $1.83B (+$359M)

7% more funds holding

Funds holding: 226242 (+16)

2.62% more ownership

Funds ownership: 100.13%102.76% (+2.6%)

0% more funds holding in top 10

Funds holding in top 10: 77 (0)

Holders
242
Holders Change
+16
Holders Change %
+7.08%
% of All Funds
2.98%
Holding in Top 10
7
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.09%
New
51
Increased
94
Reduced
53
Closed
29
Calls
$12.5M
Puts
$842K
Net Calls
+$11.7M
Net Calls Change
+$6.28M
Name Holding Trade Value Shares
Change
Change in
Stake
XT
76
XTX Topco
Cayman Islands
$1.88M +$282K +31,534 +20%
Osaic Holdings
77
Osaic Holdings
Arizona
$1.85M -$2.37K -265 -0.1%
TAM
78
TFG Asset Management
Cayman Islands
$1.81M +$1.62M +181,543 New
Squarepoint
79
Squarepoint
New York
$1.79M +$770K +86,088 +91%
RBI
80
Raiffeisen Bank International
Austria
$1.78M -$537K -60,000 -24%
Citadel Advisors
81
Citadel Advisors
Florida
$1.75M +$556K +62,122 +54%
California State Teachers Retirement System (CalSTRS)
82
California State Teachers Retirement System (CalSTRS)
California
$1.73M +$505K +56,422 +48%
State of Wisconsin Investment Board
83
State of Wisconsin Investment Board
Wisconsin
$1.61M +$546K +61,076 +60%
TE
84
Tema ETFs
New York
$1.53M +$381K +42,545 +38%
TI
85
Tidal Investments
Wisconsin
$1.53M +$1.38M +154,100 New
Rafferty Asset Management
86
Rafferty Asset Management
New York
$1.5M -$386K -43,138 -22%
Susquehanna International Group
87
Susquehanna International Group
Pennsylvania
$1.46M -$678K -75,771 -34%
AA
88
ALPS Advisors
Colorado
$1.45M +$28.4K +3,169 +2%
SA
89
Sanctuary Advisors
Indiana
$1.43M +$14.2K +1,588 +1%
EGM
90
Engineers Gate Manager
New York
$1.41M +$564K +63,084 +80%
Deutsche Bank
91
Deutsche Bank
Germany
$1.29M +$50.3K +5,618 +5%
AllianceBernstein
92
AllianceBernstein
Tennessee
$1.23M
Man Group
93
Man Group
United Kingdom
$1.12M +$231K +25,806 +30%
Wells Fargo
94
Wells Fargo
California
$1.09M -$429K -47,940 -30%
Creative Planning
95
Creative Planning
Kansas
$1.01M +$139K +15,513 +18%
IC
96
Iconiq Capital
California
$942K
TI
97
Trexquant Investment
Connecticut
$938K -$3.38M -377,797 -80%
HCS
98
Himension Capital (Singapore)
Singapore
$937K -$96.5K -10,784 -10%
VAM
99
Vanguard Asset Management
$819K +$736K +82,300 New
Legal & General Group
100
Legal & General Group
United Kingdom
$816K -$243K -27,152 -25%

RLAY Hedge Fund Activity: Q1 2026 in Review

242 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q1 2026, worth a combined $1.83B — up 24% from $1.47B a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new RLAY positions and 29 closed out — a net gain of 22 holders — while 94 added to existing stakes and 53 trimmed.

The largest buyer was Perceptive Advisors, adding an estimated $70.2M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $117M sold.

  • 242 institutional investors held Relay Therapeutics (RLAY) as of Q1 2026, up from 226 in Q4 2025.
  • Funds reported $1.83B of Relay Therapeutics stock for Q1 2026, up 24% quarter-over-quarter.
  • 51 funds opened new Relay Therapeutics positions in Q1 2026 and 29 closed out, a net change of +22 holders.
  • The largest Relay Therapeutics buyer in Q1 2026 was Perceptive Advisors, an estimated $70.2M added.
  • The largest Relay Therapeutics seller in Q1 2026 was Point72 Asset Management, an estimated $117M sold.

Based on aggregated 13F filings for Q1 2026.