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Relay Therapeutics

242 hedge funds and large institutions have $1.83B invested in Relay Therapeutics in 2026 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 94 increasing their positions, 53 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,389% more call options, than puts

Call options by funds: $12.5M | Put options by funds: $842K

77% more repeat investments, than reductions

Existing positions increased: 94 | Existing positions reduced: 53

76% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 29

24% more capital invested

Capital invested by funds: $1.47B → $1.83B (+$359M)

7% more funds holding

Funds holding: 226242 (+16)

2.62% more ownership

Funds ownership: 100.13%102.76% (+2.6%)

0% more funds holding in top 10

Funds holding in top 10: 77 (0)

Holders
242
Holders Change
+16
Holders Change %
+7.08%
% of All Funds
2.98%
Holding in Top 10
7
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.09%
New
51
Increased
94
Reduced
53
Closed
29
Calls
$12.5M
Puts
$842K
Net Calls
+$11.7M
Net Calls Change
+$6.28M
Name Holding Trade Value Shares
Change
Change in
Stake
American Century Companies
51
American Century Companies
Missouri
$4.38M +$68.8K +7,692 +2%
Jane Street
52
Jane Street
New York
$4.21M +$3.1M +347,060 +454%
HS
53
HighVista Strategies
Massachusetts
$4.2M -$1.1M -123,198 -23%
SFM
54
Sphera Funds Management
Israel
$4.06M +$3.65M +408,436 New
AAA
55
Affinity Asset Advisors
New York
$3.98M +$3.58M +400,000 New
Bank of New York Mellon
56
Bank of New York Mellon
New York
$3.81M +$37.7K +4,217 +1%
RPAM
57
Rhenman & Partners Asset Management
Sweden
$3.58M -$895K -100,000 -22%
Ameriprise
58
Ameriprise
Minnesota
$3.55M +$3.19M +356,924 New
Millennium Management
59
Millennium Management
New York
$3.46M -$4.91M -549,176 -61%
Raymond James Financial
60
Raymond James Financial
Florida
$3.45M +$777K +86,906 +34%
SPS
61
Susquehanna Portfolio Strategies
Pennsylvania
$3.37M
Hudson Bay Capital Management
62
Hudson Bay Capital Management
Connecticut
$3.1M -$1.25M -140,170 -31%
N
63
Nuveen
North Carolina
$3.01M +$15.5K +1,732 +0.6%
Acadian Asset Management
64
Acadian Asset Management
Massachusetts
$2.89M -$1.49M -166,296 -36%
EAM
65
Exome Asset Management
New York
$2.77M +$2.49M +278,302 New
EP
66
Eversept Partners
New York
$2.69M -$1.95M -218,432 -45%
SFCM
67
Seven Fleet Capital Management
California
$2.56M +$1.65M +184,738 +253%
Swiss National Bank
68
Swiss National Bank
Switzerland
$2.37M
RhumbLine Advisers
69
RhumbLine Advisers
Massachusetts
$2.16M +$10.7K +1,192 +0.6%
VOYA Investment Management
70
VOYA Investment Management
Georgia
$2.15M +$1.71M +191,477 +779%
TD Asset Management
71
TD Asset Management
Ontario, Canada
$2.13M +$288K +32,182 +18%
UBS AM
72
UBS AM
Illinois
$2.09M +$5.55K +620 +0.3%
Manulife (Manufacturers Life Insurance)
73
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.09M +$288K +32,221 +18%
IC
74
IEQ Capital
California
$2.04M +$385K +43,025 +27%
SG Americas Securities
75
SG Americas Securities
New York
$1.97M -$209K -23,414 -11%

RLAY Hedge Fund Activity: Q1 2026 in Review

242 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Relay Therapeutics (RLAY) for Q1 2026, worth a combined $1.83B — up 24% from $1.47B a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new RLAY positions and 29 closed out — a net gain of 22 holders — while 94 added to existing stakes and 53 trimmed.

The largest buyer was Perceptive Advisors, adding an estimated $70.2M. The largest seller was Point72 Asset Management, exiting entirely with an estimated $117M sold.

  • 242 institutional investors held Relay Therapeutics (RLAY) as of Q1 2026, up from 226 in Q4 2025.
  • Funds reported $1.83B of Relay Therapeutics stock for Q1 2026, up 24% quarter-over-quarter.
  • 51 funds opened new Relay Therapeutics positions in Q1 2026 and 29 closed out, a net change of +22 holders.
  • The largest Relay Therapeutics buyer in Q1 2026 was Perceptive Advisors, an estimated $70.2M added.
  • The largest Relay Therapeutics seller in Q1 2026 was Point72 Asset Management, an estimated $117M sold.

Based on aggregated 13F filings for Q1 2026.