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Protagonist Therapeutics

272 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 51 funds opening new positions, 119 increasing their positions, 77 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

0% more funds holding in top 10

Funds holding in top 10: 1414 (0)

1% less funds holding

Funds holding: 274272 (-2)

12% less call options, than puts

Call options by funds: $18.4M | Put options by funds: $20.8M

Holders
272
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$18.4M
Puts
$20.8M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Simplex Trading
176
Simplex Trading
Illinois
$522K
Aviva
177
Aviva
United Kingdom
$521K
TPSF
178
Texas Permanent School Fund
Texas
$519K
BNP Paribas Financial Markets
179
BNP Paribas Financial Markets
France
$505K
EFM
180
E Fund Management
China
$497K
CIM
181
Cambria Investment Management
California
$484K
Pathstone Holdings
182
Pathstone Holdings
New Jersey
$453K
MOACM
183
Mutual of America Capital Management
New York
$440K
PWM
184
Palumbo Wealth Management
New York
$416K
Nomura Holdings
185
Nomura Holdings
Japan
$410K
XT
186
XTX Topco
Cayman Islands
$405K
II
187
Inspire Investing
Idaho
$403K
NVCHI
188
New Vernon Capital Holdings II
New Jersey
$398K
CWM
189
CIBC World Markets
New York
$396K
Capstone Investment Advisors
190
Capstone Investment Advisors
New York
$386K
AACP
191
Advantage Alpha Capital Partners
California
$385K
BCI
192
Brinker Capital Investments
Pennsylvania
$365K
BC
193
Burney Company
Virginia
$349K
BPC
194
Bryce Point Capital
New York
$343K
KWMG
195
King Wealth Management Group
Florida
$332K
Mitsubishi UFJ Trust & Banking
196
Mitsubishi UFJ Trust & Banking
Japan
$330K
AIP
197
Ameritas Investment Partners
Nebraska
$327K
NWAG
198
Net Worth Advisory Group
Utah
$322K
KAS
199
Kestra Advisory Services
Texas
$319K
TRCT
200
Tower Research Capital (TRC)
New York
$295K