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Protagonist Therapeutics

272 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 51 funds opening new positions, 119 increasing their positions, 77 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

more capital invested

Capital invested by funds: $ → $

more ownership

Funds ownership:

more first-time investments, than exits

New positions opened: | Existing positions closed:

0% more funds holding in top 10

Funds holding in top 10: 1414 (0)

1% less funds holding

Funds holding: 274272 (-2)

12% less call options, than puts

Call options by funds: $18.4M | Put options by funds: $20.8M

Holders
272
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$18.4M
Puts
$20.8M
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
AGP
126
Artia Global Partners
Florida
$1.27M
HI
127
Horizon Investments
North Carolina
$1.24M
Mackenzie Financial
128
Mackenzie Financial
Ontario, Canada
$1.24M
Allianz Asset Management
129
Allianz Asset Management
Germany
$1.23M
GIM
130
Glenmede Investment Management
Pennsylvania
$1.18M
Comerica Bank
131
Comerica Bank
Texas
$1.18M
FCM
132
Fieldview Capital Management
Michigan
$1.13M
SO
133
STRS Ohio
Ohio
$1.08M
New York State Common Retirement Fund
134
New York State Common Retirement Fund
New York
$1.08M
BG
135
Bellevue Group
Switzerland
$1.08M
GC
136
Guggenheim Capital
Illinois
$1.06M
PA
137
Profund Advisors
Maryland
$1.05M
VRS
138
Virginia Retirement Systems
Virginia
$1.05M
CUAMC
139
China Universal Asset Management Company
China
$1.05M
TRSOTSOK
140
Teachers Retirement System of the State of Kentucky
Kentucky
$1.04M
MSRPS
141
Maryland State Retirement & Pension System
Maryland
$1.01M
Arrowstreet Capital
142
Arrowstreet Capital
Massachusetts
$987K
AB
143
Amalgamated Bank
New York
$970K
PAP
144
Persistent Asset Partners
Hong Kong
$968K
WG
145
Winton Group
United Kingdom
$964K
AQR Capital Management
146
AQR Capital Management
Connecticut
$962K
Handelsbanken Fonder
147
Handelsbanken Fonder
Sweden
$940K
SC
148
Stempoint Capital
New York
$927K
State Board of Administration of Florida Retirement System
149
State Board of Administration of Florida Retirement System
Florida
$901K
Polen Capital Management
150
Polen Capital Management
Florida
$884K