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Protagonist Therapeutics
PTGX

Overview Fund Activity

271 hedge funds and large institutions have $3.92B invested in Protagonist Therapeutics in 2025 Q2 according to their latest regulatory filings, with 50 funds opening new positions, 119 increasing their positions, 77 reducing their positions, and 49 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
271
Holders Change
-3
Holders Change %
-1.09%
% of All Funds
3.63%
Holding in Top 10
14
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.19%
New
50
Increased
119
Reduced
77
Closed
49
Calls
$18.4M
Puts
$20.8M
Net Calls
-$2.39M
Net Calls Change
-$21.6M

Top Buyers

1
UBS Group
UBS Group
Switzerland
+$119M
2
CC
Commodore Capital
New York
+$59.4M
3
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$41.4M
4
BI
BVF Inc
California
+$35.2M
5
Holocene Advisors
Holocene Advisors
New York
+$29.3M

Top Sellers

1
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$21.3M
2
Focus Partners Wealth
Focus Partners Wealth
Massachusetts
-$21M
3
NVCHI
New Vernon Capital Holdings II
New Jersey
-$18.8M
4
AGP
Artia Global Partners
Florida
-$17.2M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$15.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Wells Fargo
101
Wells Fargo
California
$2.3M +$104K +1,878 +5%
State of New Jersey Common Pension Fund D
102
State of New Jersey Common Pension Fund D
New Jersey
$2.27M -$703K -12,711 -24%
Universal-Beteiligungs- und Servicegesellschaft
103
Universal-Beteiligungs- und Servicegesellschaft
Germany
$2.24M +$2.01M +36,288 +865%
AA
104
ALPS Advisors
Colorado
$2.22M -$705K -12,754 -24%
GAM
105
Gotham Asset Management
New York
$2.06M +$786K +14,215 +62%
SOADOR
106
State of Alaska Department of Revenue
Alaska
$2.04M +$215K +3,883 +12%
TI
107
Trexquant Investment
Connecticut
$1.99M -$3.76M -67,965 -65%
Mirae Asset Global ETFs Holdings
108
Mirae Asset Global ETFs Holdings
Hong Kong
$1.98M -$86.4K -1,562 -4%
JGC
109
J. Goldman & Co
New York
$1.98M -$1.63M -29,416 -45%
MIM
110
MetLife Investment Management
New Jersey
$1.92M -$1.11K -20 -0.1%
Man Group
111
Man Group
United Kingdom
$1.88M -$5.23M -94,593 -74%
IIM
112
INTECH Investment Management
Florida
$1.88M +$164K +2,971 +10%
State of Wisconsin Investment Board
113
State of Wisconsin Investment Board
Wisconsin
$1.82M -$1.15M -20,752 -39%
Massachusetts Financial Services
114
Massachusetts Financial Services
Massachusetts
$1.78M +$21.9K +397 +1%
HSA
115
Hussman Strategic Advisors
Maryland
$1.74M -$1.16M -21,000 -40%
Creative Planning
116
Creative Planning
Kansas
$1.67M +$711K +12,871 +74%
LSERS
117
Louisiana State Employees Retirement System
Louisiana
$1.6M +$49.7K +900 +3%
IMRF
118
Illinois Municipal Retirement Fund
Illinois
$1.52M +$445K +8,060 +41%
Citadel Advisors
119
Citadel Advisors
Florida
$1.5M -$7.01M -126,866 -82%
BHCM
120
Brevan Howard Capital Management
Jersey
$1.49M +$601K +10,880 +68%
State of Tennessee, Department of Treasury
121
State of Tennessee, Department of Treasury
Tennessee
$1.44M -$27.4K -495 -2%
Envestnet Asset Management
122
Envestnet Asset Management
Illinois
$1.32M +$398K +7,199 +43%
TI
123
Tidal Investments
Wisconsin
$1.31M +$241K +4,367 +22%
YCM
124
Yousif Capital Management
Michigan
$1.29M +$59K +1,067 +5%
Ensign Peak Advisors
125
Ensign Peak Advisors
Utah
$1.28M -$216K -3,900 -14%
3 4
5
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