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Prime Medicine
PRME

Name Holding Trade Value Shares
Change 		Change in
Stake
AI
1
Alphabet Inc
California
$247M +$240M +13,284,688 New
Fidelity Investments
2
Fidelity Investments
Massachusetts
$157M +$153M +8,463,046 New
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$44.2M +$43M +2,378,582 New
RG
4
Redmile Group
California
$41M +$39.9M +2,209,350 New
MM
5
MWG Management
British Virgin Islands
$34.1M +$33.2M +1,835,876 New
Fidelity International
6
Fidelity International
Bermuda
$33.5M +$32.6M +1,805,558 New
AIM
7
ARK Investment Management
Florida
$30.5M +$29.6M +1,639,984 New
BlackRock
8
BlackRock
New York
$27.6M +$26.9M +1,487,846 New
BBA
9
Baker Bros. Advisors
New York
$19.1M +$18.6M +1,028,466 New
DM
10
Deerfield Management
New York
$16.4M +$16M +885,314 New
Vanguard Group
11
Vanguard Group
Pennsylvania
$16.2M +$15.8M +872,523 New
CC
12
Casdin Capital
New York
$13.6M +$13.3M +734,350 New
CAM
13
Cormorant Asset Management
Massachusetts
$13.6M +$13.3M +734,350 New
EC
14
EcoR1 Capital
California
$11.1M +$10.8M +600,000 New
MCM
15
Moore Capital Management
New York
$9.29M +$9.03M +500,000 New
Sumitomo Mitsui Trust Group
16
Sumitomo Mitsui Trust Group
Japan
$9.07M +$8.82M +488,226 New
NAMA
17
Nikko Asset Management Americas
New York
$9.04M +$8.82M +488,226 New
SB
18
Samsara BioCapital
California
$8.74M +$8.5M +470,304 New
Geode Capital Management
19
Geode Capital Management
Massachusetts
$4.35M +$4.23M +234,295 New
Ensign Peak Advisors
20
Ensign Peak Advisors
Utah
$2.79M +$2.71M +150,000 New
OMC
21
OUP Management Company
Pennsylvania
$2.25M +$2.19M +121,255 New
State Street
22
State Street
Massachusetts
$2.13M +$2.07M +114,846 New
CCM
23
CAAS Capital Management
New York
$1.66M +$1.61M +89,331 New
Northern Trust
24
Northern Trust
Illinois
$1.55M +$1.51M +83,546 New
Charles Schwab
25
Charles Schwab
California
$1.32M +$1.29M +71,184 New
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