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Prime Medicine
PRME

Name Holding Trade Value Shares
Change 		Change in
Stake
AI
1
Alphabet Inc
California
$91.8M +$6.09M +1,500,000 +10%
T. Rowe Price Investment Management
2
T. Rowe Price Investment Management
Maryland
$51.1M +$11.1M +2,732,310 +42%
BlackRock
3
BlackRock
New York
$31.3M +$4.73M +1,165,031 +26%
AIM
4
ARK Investment Management
Florida
$30.3M +$12.8M +3,155,182 +136%
Vanguard Group
5
Vanguard Group
Pennsylvania
$27.3M +$5.26M +1,294,355 +36%
FCM
6
Farallon Capital Management
California
$26.3M +$16.3M +4,000,000 +533%
Sumitomo Mitsui Trust Group
7
Sumitomo Mitsui Trust Group
Japan
$20.1M +$8.27M +2,035,406 +128%
NAMA
8
Nikko Asset Management Americas
New York
$20M +$8.29M +2,040,807 +128%
CC
9
Casdin Capital
New York
$17.5M +$6.5M +1,600,000 +102%
WP
10
Woodline Partners
California
$16.6M +$12.2M +3,002,482 New
RCM
11
RA Capital Management
Massachusetts
$16.6M +$12.2M +3,000,000 New
Fidelity Investments
12
Fidelity Investments
Massachusetts
$15.6M -$3.78M -931,352 -25%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$12.3M +$9M +2,215,852 New
MM
14
MWG Management
British Virgin Islands
$9.93M – – –
Geode Capital Management
15
Geode Capital Management
Massachusetts
$9.79M +$1.04M +256,147 +17%
EC
16
EcoR1 Capital
California
$8.55M +$6.27M +1,543,326 New
Millennium Management
17
Millennium Management
New York
$7.86M +$5.16M +1,270,467 +858%
State Street
18
State Street
Massachusetts
$7.18M +$233K +57,289 +5%
Renaissance Technologies
19
Renaissance Technologies
New York
$6.29M +$3.7M +911,270 +408%
Citadel Advisors
20
Citadel Advisors
Florida
$4.99M +$1.54M +378,634 +73%
Adage Capital Partners
21
Adage Capital Partners
Massachusetts
$4.27M +$3.13M +771,361 New
Invesco
22
Invesco
Georgia
$4.22M +$3.04M +748,416 +5,478%
Morgan Stanley
23
Morgan Stanley
New York
$4.05M +$582K +143,328 +24%
GWM
24
Greenwich Wealth Management
Connecticut
$3.99M -$513K -126,200 -15%
Northern Trust
25
Northern Trust
Illinois
$3.37M +$389K +95,755 +19%
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