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Prelude Therapeutics

62 hedge funds and large institutions have $41M invested in Prelude Therapeutics in 2024 Q4 according to their latest regulatory filings, with 8 funds opening new positions, 26 increasing their positions, 12 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

117% more repeat investments, than reductions

Existing positions increased: 26 | Existing positions reduced: 12

8.54% less ownership

Funds ownership: 84.79%76.25% (-8.5%)

11% less funds holding

Funds holding: 7062 (-8)

45% less capital invested

Capital invested by funds: $74M → $41M (-$33M)

50% less first-time investments, than exits

New positions opened: 8 | Existing positions closed: 16

Holders
62
Holders Change
-8
Holders Change %
-11.43%
% of All Funds
0.82%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
8
Increased
26
Reduced
12
Closed
16
Calls
$8K
Puts
Net Calls
+$8K
Net Calls Change
+$8K
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$13.9M
BBA
2
Baker Bros. Advisors
New York
$12.9M
BCM
3
Boxer Capital Management
California
$2.18M +$2.27M +1,708,187 New
BlackRock
4
BlackRock
New York
$1.36M +$15.2K +11,457 +1%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$1.31M -$90.8K -68,400 -6%
Vanguard Group
6
Vanguard Group
Pennsylvania
$1.29M -$15.1K -11,378 -1%
Jacobs Levy Equity Management
7
Jacobs Levy Equity Management
New Jersey
$850K +$652K +491,595 +281%
Renaissance Technologies
8
Renaissance Technologies
New York
$809K +$581K +437,600 +222%
Massachusetts Financial Services
9
Massachusetts Financial Services
Massachusetts
$630K -$73K -55,033 -10%
Acadian Asset Management
10
Acadian Asset Management
Massachusetts
$617K +$546K +411,238 +555%
Millennium Management
11
Millennium Management
New York
$590K +$401K +302,031 +188%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$513K +$14.1K +10,620 +3%
Marshall Wace
13
Marshall Wace
United Kingdom
$498K +$43.8K +33,018 +9%
Morgan Stanley
14
Morgan Stanley
New York
$466K +$55K +41,470 +13%
Two Sigma Advisers
15
Two Sigma Advisers
New York
$383K +$335K +252,100 +526%
State Street
16
State Street
Massachusetts
$374K +$9.75K +7,350 +3%
Two Sigma Investments
17
Two Sigma Investments
New York
$296K +$232K +174,906 +307%
RhumbLine Advisers
18
RhumbLine Advisers
Massachusetts
$213K +$205K +154,826 +1,290%
TD Asset Management
19
TD Asset Management
Ontario, Canada
$205K
Goldman Sachs
20
Goldman Sachs
New York
$189K +$70.5K +53,165 +56%
Deutsche Bank
21
Deutsche Bank
Germany
$159K +$145K +109,281 +748%
Charles Schwab
22
Charles Schwab
California
$149K -$21.3K -16,049 -12%
BCM
23
Bridgeway Capital Management
Texas
$142K -$86.4K -65,100 -37%
Northern Trust
24
Northern Trust
Illinois
$106K -$30.5K -22,990 -22%
Susquehanna International Group
25
Susquehanna International Group
Pennsylvania
$92.8K +$96.6K +72,799 New

PRLD Hedge Fund Activity: Q4 2024 in Review

62 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in Prelude Therapeutics (PRLD) for Q4 2024, worth a combined $41M — down 45% from $74M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of PRLD and 8 opened new positions — a net loss of 8 holders — while 12 trimmed existing stakes and 26 added.

The largest buyer was Jacobs Levy Equity Management, adding an estimated $652K. The largest seller was Deerfield Management, exiting entirely with an estimated $7.8M sold.

  • 62 institutional investors held Prelude Therapeutics (PRLD) as of Q4 2024, down from 70 in Q3 2024.
  • Funds reported $41M of Prelude Therapeutics stock for Q4 2024, down 45% quarter-over-quarter.
  • 8 funds opened new Prelude Therapeutics positions in Q4 2024 and 16 closed out, a net change of -8 holders.
  • The largest Prelude Therapeutics buyer in Q4 2024 was Jacobs Levy Equity Management, an estimated $652K added.
  • The largest Prelude Therapeutics seller in Q4 2024 was Deerfield Management, an estimated $7.8M sold.

Based on aggregated 13F filings for Q4 2024.