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Prelude Therapeutics

75 hedge funds and large institutions have $438M invested in Prelude Therapeutics in 2021 Q4 according to their latest regulatory filings, with 26 funds opening new positions, 27 increasing their positions, 14 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

117% more first-time investments, than exits

New positions opened: 26 | Existing positions closed: 12

93% more repeat investments, than reductions

Existing positions increased: 27 | Existing positions reduced: 14

84% more call options, than puts

Call options by funds: $68K | Put options by funds: $37K

23% more funds holding

Funds holding: 6175 (+14)

2.7% less ownership

Funds ownership: 100.92%98.22% (-2.7%)

61% less capital invested

Capital invested by funds: $1.12B → $438M (-$686M)

100% less funds holding in top 10

Funds holding in top 10: 20 (-2)

Holders
75
Holders Change
+14
Holders Change %
+22.95%
% of All Funds
1.15%
Holding in Top 10
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-100%
% of All Funds
New
26
Increased
27
Reduced
14
Closed
12
Calls
$68K
Puts
$37K
Net Calls
+$31K
Net Calls Change
+$31K
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$126M
O
2
OrbiMed
New York
$125M
Fidelity Investments
3
Fidelity Investments
Massachusetts
$73.9M -$18.2M -1,116,733 -16%
UBS AM
4
UBS AM
Illinois
$18.8M +$494K +30,367 +2%
BlackRock
5
BlackRock
New York
$11.2M +$2.77M +170,542 +23%
Morgan Stanley
6
Morgan Stanley
New York
$10.5M +$1.45M +88,927 +12%
Vanguard Group
7
Vanguard Group
Pennsylvania
$9.6M -$5.94M -365,282 -32%
HA
8
HHLR Advisors
Cayman Islands
$7.26M
Massachusetts Financial Services
9
Massachusetts Financial Services
Massachusetts
$5.84M -$56.1K -3,449 -0.7%
Millennium Management
10
Millennium Management
New York
$5.53M +$6.56M +403,260 +987%
RSCM
11
Rock Springs Capital Management
Maryland
$4.59M +$107K +6,600 +2%
T. Rowe Price Associates
12
T. Rowe Price Associates
Maryland
$3.79M -$1.48M -90,944 -23%
Two Sigma Investments
13
Two Sigma Investments
New York
$3.52M +$4.6M +282,774 New
Marshall Wace
14
Marshall Wace
United Kingdom
$3.34M +$4.36M +268,018 New
Geode Capital Management
15
Geode Capital Management
Massachusetts
$2.65M -$594K -36,536 -15%
State Street
16
State Street
Massachusetts
$2.6M -$10.4M -642,077 -75%
Citadel Advisors
17
Citadel Advisors
Florida
$1.73M +$2.02M +124,005 +856%
Jacobs Levy Equity Management
18
Jacobs Levy Equity Management
New Jersey
$1.62M +$2.12M +130,280 New
Renaissance Technologies
19
Renaissance Technologies
New York
$1.58M +$2.07M +127,200 New
CSS
20
Cubist Systematic Strategies
Connecticut
$1.45M +$1.54M +94,548 +435%
HF
21
HRT Financial
New York
$1.42M +$1.61M +98,690 +634%
Goldman Sachs
22
Goldman Sachs
New York
$1.41M +$1.7M +104,676 +1,209%
Northern Trust
23
Northern Trust
Illinois
$1.33M +$12.3K +759 +0.7%
Charles Schwab
24
Charles Schwab
California
$1.06M +$18.7K +1,152 +1%
Two Sigma Advisers
25
Two Sigma Advisers
New York
$1.05M +$1.37M +84,300 New

PRLD Hedge Fund Activity: Q4 2021 in Review

75 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Prelude Therapeutics (PRLD) for Q4 2021, worth a combined $438M — down 61% from $1.12B a quarter earlier.

Buyers outnumbered sellers: 26 funds opened new PRLD positions and 12 closed out — a net gain of 14 holders — while 27 added to existing stakes and 14 trimmed.

The largest buyer was Millennium Management, adding an estimated $6.56M. The largest seller was Fidelity Investments, cutting an estimated $18.2M.

  • 75 institutional investors held Prelude Therapeutics (PRLD) as of Q4 2021, up from 61 in Q3 2021.
  • Funds reported $438M of Prelude Therapeutics stock for Q4 2021, down 61% quarter-over-quarter.
  • 26 funds opened new Prelude Therapeutics positions in Q4 2021 and 12 closed out, a net change of +14 holders.
  • The largest Prelude Therapeutics buyer in Q4 2021 was Millennium Management, an estimated $6.56M added.
  • The largest Prelude Therapeutics seller in Q4 2021 was Fidelity Investments, an estimated $18.2M sold.

Based on aggregated 13F filings for Q4 2021.