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Prelude Therapeutics
PRLD

Overview Fund Activity

48 hedge funds and large institutions have $22M invested in Prelude Therapeutics in 2025 Q2 according to their latest regulatory filings, with 7 funds opening new positions, 12 increasing their positions, 22 reducing their positions, and 16 closing their positions.

Holders
48
Holders Change
-10
Holders Change %
-17.24%
% of All Funds
0.64%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
7
Increased
12
Reduced
22
Closed
16
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
CF
1
Cantor Fitzgerald
New York
$171K
2
Millennium Management
2
Millennium Management
New York
$201K
3
Jane Street
3
Jane Street
New York
$74.3K
4
SC
4
Shay Capital
New York
$60.7K
5
GCP
5
GSA Capital Partners
United Kingdom
$58K

Top Sellers

1
NL
1
Nuveen LLC
North Carolina
$0
2
BCM
2
Boxer Capital Management
California
$0
3
BlackRock
3
BlackRock
New York
$350K
4
State Street
4
State Street
Massachusetts
$79K
5
Geode Capital Management
5
Geode Capital Management
Massachusetts
$176K
Name Market Value Shares Shares
Change 		Shares
Change %
O
1
OrbiMed
New York
$8.83M 10,909,256 – –
BBA
2
Baker Bros. Advisors
New York
$8.19M 10,123,824 – –
Vanguard Group
3
Vanguard Group
Pennsylvania
$754K 932,570 -76,634 -8%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$743K 927,608 -48,539 -5%
Renaissance Technologies
5
Renaissance Technologies
New York
$471K 581,800 -74,900 -11%
Acadian Asset Management
6
Acadian Asset Management
Massachusetts
$436K 540,565 +11,238 +2%
BlackRock
7
BlackRock
New York
$350K 432,559 -615,166 -59%
Morgan Stanley
8
Morgan Stanley
New York
$230K 284,382 -18,397 -6%
Millennium Management
9
Millennium Management
New York
$201K 248,423 +101,653 +69%
Two Sigma Advisers
10
Two Sigma Advisers
New York
$182K 225,000 -35,400 -14%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$176K 217,568 -187,387 -46%
CF
12
Cantor Fitzgerald
New York
$171K 211,859 +211,859 New
TD Asset Management
13
TD Asset Management
Ontario, Canada
$130K 160,652 – –
Two Sigma Investments
14
Two Sigma Investments
New York
$125K 154,977 -28,690 -16%
Goldman Sachs
15
Goldman Sachs
New York
$121K 149,178 -6,037 -4%
UBS Group
16
UBS Group
Switzerland
$84.3K 104,204 +8,048 +8%
State Street
17
State Street
Massachusetts
$79K 97,592 -188,454 -66%
Jane Street
18
Jane Street
New York
$74.3K 91,753 +91,753 New
BCM
19
Bridgeway Capital Management
Texas
$71.6K 88,500 – –
Charles Schwab
20
Charles Schwab
California
$65.4K 80,845 -33,205 -29%
SC
21
Shay Capital
New York
$60.7K 75,000 +75,000 New
GCP
22
GSA Capital Partners
United Kingdom
$58K 71,378 +71,378 New
Manulife (Manufacturers Life Insurance)
23
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$56.1K 69,252 – –
YIH
24
Y-Intercept (HK)
Hong Kong
$38.7K 47,788 +47,788 New
AQR Capital Management
25
AQR Capital Management
Connecticut
$35.3K 43,647 +9,824 +29%
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