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Prelude Therapeutics
PRLD

60 hedge funds and large institutions have $1.41B invested in Prelude Therapeutics in 2021 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 30 increasing their positions, 8 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

275% more repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 8

113% more first-time investments, than exits

New positions opened: 17 | Existing positions closed: 8

18% more funds holding

Funds holding: 51 → 60 (+9)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

9.44% less ownership

Funds ownership: 79.29% → 69.85% (-9.4%)

43% less capital invested

Capital invested by funds: $2.47B → $1.41B (-$1.06B)

Holders
60
Holders Change
+9
Holders Change %
+17.65%
% of All Funds
1.05%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
17
Increased
30
Reduced
8
Closed
8
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
Fidelity Investments
Fidelity Investments
Massachusetts
+$135M
2
State Street
State Street
Massachusetts
+$48.5M
3
Vanguard Group
Vanguard Group
Pennsylvania
+$13.8M
4
Federated Hermes
Federated Hermes
Pennsylvania
+$12.3M
5
UBS AM
UBS AM
Illinois
+$8.42M

Top Sellers

Rank Fund Capital Flow
1
O
OrbiMed
New York
-$369M
2
HA
HHLR Advisors
Cayman Islands
-$8.19M
3
SCM
Suvretta Capital Management
New York
-$7.95M
4
CCM
CAAS Capital Management
New York
-$3.58M
5
Squarepoint
Squarepoint
New York
-$1.48M
Name Holding Trade Value Shares
Change 		Change in
Stake
UBS Group
26
UBS Group
Switzerland
$968K +$1.31M +19,755 +765%
Citadel Advisors
27
Citadel Advisors
Florida
$845K +$1.29M +19,496 New
California Public Employees Retirement System
28
California Public Employees Retirement System
California
$764K -$110K -1,652 -9%
Ensign Peak Advisors
29
Ensign Peak Advisors
Utah
$758K +$1.16M +17,498 New
Bank Julius Baer & Co
30
Bank Julius Baer & Co
Switzerland
$750K +$1.15M +17,312 New
Bank of America
31
Bank of America
North Carolina
$711K +$1.06M +15,931 +3,251%
California State Teachers Retirement System (CalSTRS)
32
California State Teachers Retirement System (CalSTRS)
California
$648K +$70.3K +1,059 +8%
Millennium Management
33
Millennium Management
New York
$585K +$896K +13,503 New
State of Wisconsin Investment Board
34
State of Wisconsin Investment Board
Wisconsin
$576K +$882K +13,300 New
D.E. Shaw & Co
35
D.E. Shaw & Co
New York
$544K +$832K +12,546 New
AllianceBernstein
36
AllianceBernstein
Tennessee
$451K +$119K +1,800 +21%
RhumbLine Advisers
37
RhumbLine Advisers
Massachusetts
$419K +$7.63K +115 +1%
New York State Common Retirement Fund
38
New York State Common Retirement Fund
New York
$390K +$119K +1,800 +25%
AIP
39
ARS Investment Partners
New York
$321K – – –
CSS
40
Cubist Systematic Strategies
Connecticut
$277K +$424K +6,395 New
JP Morgan Chase
41
JP Morgan Chase
New York
$273K -$1.21M -18,201 -74%
JF
42
Jump Financial
Illinois
$273K +$418K +6,300 New
Manulife (Manufacturers Life Insurance)
43
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$239K +$15.1K +227 +4%
PPA
44
Parametric Portfolio Associates
Washington
$224K +$344K +5,178 New
PL
45
Parkwood LLC
Ohio
$218K +$334K +5,037 New
MIM
46
MetLife Investment Management
New Jersey
$180K +$1.92K +29 +0.7%
Royal Bank of Canada
47
Royal Bank of Canada
Ontario, Canada
$150K +$41K +618 +22%
MLICM
48
Metropolitan Life Insurance Company (MetLife)
New York
$125K – – –
TRCT
49
Tower Research Capital (TRC)
New York
$122K +$172K +2,600 +1,268%
SO
50
STRS Ohio
Ohio
$95K – – –
1
2
3

PRLD Hedge Fund Activity: Q1 2021 in Review

60 of the 5,695 institutional investors tracked by Wall St. Rank reported a position in Prelude Therapeutics (PRLD) for Q1 2021, worth a combined $1.41B — down 43% from $2.47B a quarter earlier.

Buyers outnumbered sellers: 17 funds opened new PRLD positions and 8 closed out — a net gain of 9 holders — while 30 added to existing stakes and 8 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $135M. The largest seller was OrbiMed, cutting an estimated $369M.

  • 60 institutional investors held Prelude Therapeutics (PRLD) as of Q1 2021, up from 51 in Q4 2020.
  • Funds reported $1.41B of Prelude Therapeutics stock for Q1 2021, down 43% quarter-over-quarter.
  • 17 funds opened new Prelude Therapeutics positions in Q1 2021 and 8 closed out, a net change of +9 holders.
  • The largest Prelude Therapeutics buyer in Q1 2021 was Fidelity Investments, an estimated $135M added.
  • The largest Prelude Therapeutics seller in Q1 2021 was OrbiMed, an estimated $369M sold.

Based on aggregated 13F filings for Q1 2021.