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Pliant Therapeutics

114 hedge funds and large institutions have $59.7M invested in Pliant Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 30 increasing their positions, 39 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

22% more call options, than puts

Call options by funds: $133K | Put options by funds: $109K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

10.65% less ownership

Funds ownership: 94.53%83.88% (-11%)

19% less funds holding

Funds holding: 140114 (-26)

23% less repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 39

24% less capital invested

Capital invested by funds: $78.5M → $59.7M (-$18.8M)

52% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 50

Holders
114
Holders Change
-26
Holders Change %
-18.57%
% of All Funds
1.5%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
24
Increased
30
Reduced
39
Closed
50
Calls
$133K
Puts
$109K
Net Calls
+$24K
Net Calls Change
-$180K
Name Holding Trade Value Shares
Change
Change in
Stake
Jane Street
26
Jane Street
New York
$375K +$264K +186,696 +137%
Dimensional Fund Advisors
27
Dimensional Fund Advisors
Texas
$367K -$277K -195,831 -38%
SEI Investments
28
SEI Investments
Pennsylvania
$345K +$71K +50,283 +20%
ACH
29
ArrowMark Colorado Holdings
Colorado
$326K
Two Sigma Investments
30
Two Sigma Investments
New York
$323K +$4.06K +2,871 +1%
CSS
31
Cubist Systematic Strategies
Connecticut
$311K +$379K +268,353 New
State Street
32
State Street
Massachusetts
$294K -$1.45M -1,025,860 -80%
Charles Schwab
33
Charles Schwab
California
$292K -$195K -137,984 -35%
Renaissance Technologies
34
Renaissance Technologies
New York
$232K +$67K +47,448 +31%
CWM
35
Congress Wealth Management
Massachusetts
$232K -$314K -222,391 -53%
Susquehanna International Group
36
Susquehanna International Group
Pennsylvania
$197K +$104K +73,519 +76%
Northern Trust
37
Northern Trust
Illinois
$192K -$486K -343,641 -68%
RHJA
38
Rice Hall James & Associates
California
$187K +$11.7K +8,254 +5%
Squarepoint
39
Squarepoint
New York
$183K +$5.86K +4,149 +3%
BNP Paribas Financial Markets
40
BNP Paribas Financial Markets
France
$179K -$42K -29,702 -16%
Qube Research & Technologies (QRT)
41
Qube Research & Technologies (QRT)
United Kingdom
$176K +$214K +151,662 New
JG
42
Jain Global
New York
$164K +$152K +107,476 +316%
HWM
43
HighMark Wealth Management
Minnesota
$164K -$23.3K -16,500 -10%
BDFN
44
Bond & Devick Financial Network
Minnesota
$116K
HWAM
45
Hennion & Walsh Asset Management
New Jersey
$116K -$6.51K -4,611 -4%
AG
46
Algert Global
California
$103K
Federated Hermes
47
Federated Hermes
Pennsylvania
$99.1K +$37K +26,212 +44%
T. Rowe Price Associates
48
T. Rowe Price Associates
Maryland
$98K -$5.38K -3,806 -4%
BCM
49
Bridgeway Capital Management
Texas
$95.5K +$116K +82,300 New
ACM
50
ADAR1 Capital Management
Texas
$95.3K +$116K +82,189 New

PLRX Hedge Fund Activity: Q2 2025 in Review

114 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q2 2025, worth a combined $59.7M — down 24% from $78.5M a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of PLRX and 24 opened new positions — a net loss of 26 holders — while 39 trimmed existing stakes and 30 added.

The largest buyer was Citadel Advisors, adding an estimated $3.33M. The largest seller was BlackRock, cutting an estimated $4.4M.

  • 114 institutional investors held Pliant Therapeutics (PLRX) as of Q2 2025, down from 140 in Q1 2025.
  • Funds reported $59.7M of Pliant Therapeutics stock for Q2 2025, down 24% quarter-over-quarter.
  • 24 funds opened new Pliant Therapeutics positions in Q2 2025 and 50 closed out, a net change of -26 holders.
  • The largest Pliant Therapeutics buyer in Q2 2025 was Citadel Advisors, an estimated $3.33M added.
  • The largest Pliant Therapeutics seller in Q2 2025 was BlackRock, an estimated $4.4M sold.

Based on aggregated 13F filings for Q2 2025.