PepGen
PEPG
87 hedge funds and large institutions have $373M invested in PepGen in 2025 Q4 according to their latest regulatory filings, with 29 funds opening new positions, 27 increasing their positions, 17 reducing their positions, and 12 closing their positions.
200% more call options, than puts
Call options by funds: $5.31M | Put options by funds: $1.77M
142% more first-time investments, than exits
New positions opened: 29 | Existing positions closed: 12
59% more repeat investments, than reductions
Existing positions increased: 27 | Existing positions reduced: 17
43% more capital invested
Capital invested by funds: $262M → $373M (+$111M)
21% more funds holding
Funds holding: 72 → 87 (+15)
89.51% less ownership
Funds ownership: 172.95% → 83.44% (-90%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
NCM
Nantahala Capital Management
New Canaan,
Connecticut
|
+$8.03M |
| 2 |
CC
Commodore Capital
New York
|
+$5.41M |
| 3 |
Pictet Asset Management
Carouge,
Switzerland
|
+$4.52M |
| 4 |
BlackRock
New York
|
+$4.07M |
| 5 |
Morgan Stanley
New York
|
+$2.64M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Adage Capital Partners
Boston,
Massachusetts
|
-$7.01M |
| 2 |
RI
RTW Investments
New York
|
-$6.93M |
| 3 |
DTC
Deep Track Capital
Greenwich,
Connecticut
|
-$5.54M |
| 4 |
TCM
TCG Crossover Management
Palo Alto,
California
|
-$5.54M |
| 5 |
EC
EcoR1 Capital
San Francisco,
California
|
-$3.7M |
PEPG Hedge Fund Activity: Q4 2025 in Review
87 of the 8,226 institutional investors tracked by Wall St. Rank reported a position in PepGen (PEPG) for Q4 2025, worth a combined $373M — up 43% from $262M a quarter earlier.
Buyers outnumbered sellers: 29 funds opened new PEPG positions and 12 closed out — a net gain of 17 holders — while 27 added to existing stakes and 17 trimmed.
The largest buyer was Nantahala Capital Management, opening a new position worth an estimated $8.03M. The largest seller was Adage Capital Partners, cutting an estimated $7.01M.
- 87 institutional investors held PepGen (PEPG) as of Q4 2025, up from 72 in Q3 2025.
- Funds reported $373M of PepGen stock for Q4 2025, up 43% quarter-over-quarter.
- 29 funds opened new PepGen positions in Q4 2025 and 12 closed out, a net change of +17 holders.
- The largest PepGen buyer in Q4 2025 was Nantahala Capital Management, an estimated $8.03M added.
- The largest PepGen seller in Q4 2025 was Adage Capital Partners, an estimated $7.01M sold.
Based on aggregated 13F filings for Q4 2025.