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PepGen
PEPG

72 hedge funds and large institutions have $262M invested in PepGen in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 19 increasing their positions, 19 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

916% more capital invested

Capital invested by funds: $25.8M → $262M (+$236M)

597% more call options, than puts

Call options by funds: $5.9M | Put options by funds: $846K

167% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 12

101.96% more ownership

Funds ownership: 70.99% → 172.95% (+102%)

38% more funds holding

Funds holding: 52 → 72 (+20)

0% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 19

Holders
72
Holders Change
+20
Holders Change %
+38.46%
% of All Funds
0.94%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
32
Increased
19
Reduced
19
Closed
12
Calls
$5.9M
Puts
$846K
Net Calls
+$5.05M
Net Calls Change
+$5.04M

Top Buyers

Rank Fund Capital Flow
1
RCM
RA Capital Management
Massachusetts
+$15.1M
2
CC
Commodore Capital
New York
+$3.8M
3
VC
Vivo Capital
California
+$3.75M
4
Viking Global Investors
Viking Global Investors
Connecticut
+$3.22M
5
BI
BVF Inc
California
+$3.09M

Top Sellers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
-$1.63M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
-$1.18M
3
SCM
Suvretta Capital Management
New York
-$333K
4
BlackRock
BlackRock
New York
-$319K
5
PM
Prosight Management
Texas
-$271K
Name Holding Trade Value Shares
Change 		Change in
Stake
BlackRock
26
BlackRock
New York
$2.08M -$319K -197,895 -31%
SC
27
Stempoint Capital
New York
$1.8M +$627K +389,189 New
BFM
28
Boothbay Fund Management
New York
$1.62M +$491K +304,815 +669%
DCM
29
Driehaus Capital Management
Illinois
$1.46M +$508K +315,000 New
MIM
30
Monashee Investment Management
Massachusetts
$1.39M +$484K +300,000 New
Citadel Advisors
31
Citadel Advisors
Florida
$1.37M +$479K +297,258 New
BCM
32
Boxer Capital Management
California
$1.16M +$403K +250,000 New
UBS Group
33
UBS Group
Switzerland
$1.12M +$369K +229,089 +1,714%
Geode Capital Management
34
Geode Capital Management
Massachusetts
$928K -$588 -365 -0.2%
ECM
35
ExodusPoint Capital Management
New York
$879K +$307K +190,256 New
SFM
36
Sphera Funds Management
Israel
$792K +$24.2K +15,000 +10%
Acadian Asset Management
37
Acadian Asset Management
Massachusetts
$693K +$242K +150,192 New
Susquehanna International Group
38
Susquehanna International Group
Pennsylvania
$608K +$144K +89,327 +211%
MCM
39
Monimus Capital Management
New Jersey
$484K +$169K +104,800 New
RC
40
RBF Capital
California
$462K – – –
Two Sigma Investments
41
Two Sigma Investments
New York
$427K +$46.3K +28,753 +45%
Renaissance Technologies
42
Renaissance Technologies
New York
$350K +$39.3K +24,400 +48%
OM
43
Opaleye Management
Massachusetts
$347K -$266K -165,000 -69%
FLC
44
Fifth Lane Capital
Texas
$323K +$113K +70,000 New
State Street
45
State Street
Massachusetts
$304K -$5.4K -3,350 -5%
BCM
46
Bridgeway Capital Management
Texas
$291K -$46.6K -28,923 -31%
Northern Trust
47
Northern Trust
Illinois
$275K +$18.6K +11,540 +24%
GCP
48
GSA Capital Partners
United Kingdom
$213K +$74.4K +46,158 New
RC
49
Rangeley Capital
Connecticut
$203K +$14.5K +9,000 +26%
Connor, Clark & Lunn Investment Management (CC&L)
50
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$176K +$61.4K +38,081 New
1
2
3 4

PEPG Hedge Fund Activity: Q3 2025 in Review

72 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in PepGen (PEPG) for Q3 2025, worth a combined $262M — up 916% from $25.8M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new PEPG positions and 12 closed out — a net gain of 20 holders — while 19 added to existing stakes and 19 trimmed.

The largest buyer was RA Capital Management, adding an estimated $15.1M. The largest seller was Millennium Management, cutting an estimated $1.63M.

  • 72 institutional investors held PepGen (PEPG) as of Q3 2025, up from 52 in Q2 2025.
  • Funds reported $262M of PepGen stock for Q3 2025, up 916% quarter-over-quarter.
  • 32 funds opened new PepGen positions in Q3 2025 and 12 closed out, a net change of +20 holders.
  • The largest PepGen buyer in Q3 2025 was RA Capital Management, an estimated $15.1M added.
  • The largest PepGen seller in Q3 2025 was Millennium Management, an estimated $1.63M sold.

Based on aggregated 13F filings for Q3 2025.