|
1
|
Franklin Resources
San Mateo,
California
|
$31.5M
|
+$327K
|
+1,441
|
+1%
|
|
|
2
|
New Leaf Venture Partners
New York
|
$29.3M
|
–
|
–
|
–
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
$27M
|
-$1.29M
|
-5,685
|
-5%
|
|
|
4
|
VHCP Management II
New York
|
$24.2M
|
–
|
–
|
–
|
|
|
5
|
Acuta Capital Partners
Redwood City,
California
|
$13M
|
+$3.83M
|
+16,863
|
+48%
|
|
|
6
|
Eagle Asset Management
St Petersburg,
Florida
|
$10.8M
|
+$260K
|
+1,146
|
+3%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$8.5M
|
+$132K
|
+580
|
+2%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$6.46M
|
+$811K
|
+3,570
|
+16%
|
|
|
9
|
Opaleye Management
Boston,
Massachusetts
|
$3.5M
|
–
|
–
|
–
|
|
|
10
|
Millennium Management
New York
|
$3.48M
|
-$28.2K
|
-124
|
-0.9%
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
$2.61M
|
–
|
–
|
–
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$2.5M
|
+$123K
|
+543
|
+6%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$2.06M
|
+$35.2K
|
+155
|
+2%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$2.05M
|
+$98.8K
|
+435
|
+6%
|
|
|
15
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.88M
|
–
|
–
|
–
|
|
|
16
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.83M
|
+$69.5K
|
+306
|
+4%
|
|
|
17
|
|
$1.69M
|
–
|
–
|
–
|
|
|
18
|
|
$1.6M
|
+$29.1K
|
+128
|
+2%
|
|
|
19
|
Charles Schwab
San Francisco,
California
|
$875K
|
+$49.1K
|
+216
|
+7%
|
|
|
20
|
BlackRock Investment Management
Wilmington,
Delaware
|
$810K
|
-$1.82K
|
-8
|
-0.2%
|
|
|
21
|
Bank of New York Mellon
New York
|
$764K
|
+$106K
|
+466
|
+18%
|
|
|
22
|
|
$602K
|
+$291K
|
+1,282
|
+114%
|
|
|
23
|
Raymond James Financial Services Advisors
St. Petersburg,
Florida
|
$588K
|
–
|
–
|
–
|
|
|
24
|
TIAA CREF Investment Management
New York
|
$577K
|
+$10.7K
|
+47
|
+2%
|
|
|
25
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$418K
|
-$10.2K
|
-45
|
-3%
|
|
