|
1
|
Franklin Resources
San Mateo,
California
|
$26M
|
+$1.01M
|
+5,105
|
+4%
|
|
|
2
|
New Leaf Venture Partners
New York
|
$24.4M
|
–
|
–
|
–
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
$23.7M
|
-$568K
|
-2,866
|
-2%
|
|
|
4
|
VHCP Management II
New York
|
$20.1M
|
–
|
–
|
–
|
|
|
5
|
Eagle Asset Management
St Petersburg,
Florida
|
$8.74M
|
+$230K
|
+1,161
|
+3%
|
|
|
6
|
Acuta Capital Partners
Redwood City,
California
|
$7.32M
|
+$1.71M
|
+8,650
|
+33%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.96M
|
+$2.02M
|
+10,184
|
+44%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$4.64M
|
+$288K
|
+1,456
|
+7%
|
|
|
9
|
Millennium Management
New York
|
$2.92M
|
+$315K
|
+1,592
|
+13%
|
|
|
10
|
Opaleye Management
Boston,
Massachusetts
|
$2.92M
|
+$539K
|
+2,720
|
+24%
|
|
|
11
|
Asset Management One
Tokyo,
Japan
|
$2.31M
|
-$229K
|
-1,157
|
-9%
|
|
|
12
|
Fidelity Investments
Boston,
Massachusetts
|
$2.18M
|
–
|
–
|
–
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$1.97M
|
+$309K
|
+1,562
|
+20%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$1.68M
|
+$854K
|
+4,308
|
+115%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$1.61M
|
+$62.6K
|
+316
|
+4%
|
|
|
16
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.56M
|
–
|
–
|
–
|
|
|
17
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.46M
|
+$35.1K
|
+177
|
+3%
|
|
|
18
|
|
$1.41M
|
–
|
–
|
–
|
|
|
19
|
|
$1.3M
|
+$83.8K
|
+423
|
+7%
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$684K
|
+$257K
|
+1,296
|
+65%
|
|
|
21
|
BlackRock Investment Management
Wilmington,
Delaware
|
$676K
|
-$793
|
-4
|
-0.1%
|
|
|
22
|
Bank of New York Mellon
New York
|
$539K
|
+$64.2K
|
+324
|
+14%
|
|
|
23
|
Raymond James Financial Services Advisors
St. Petersburg,
Florida
|
$489K
|
+$9.91K
|
+50
|
+2%
|
|
|
24
|
TIAA CREF Investment Management
New York
|
$471K
|
-$18.4K
|
-93
|
-4%
|
|
|
25
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$358K
|
+$2.97K
|
+15
|
+0.9%
|
|
