|
1
|
Franklin Resources
San Mateo,
California
|
$24.2M
|
-$7.07K
|
-40
|
-0%
|
|
|
2
|
New Leaf Venture Partners
New York
|
$23.7M
|
–
|
–
|
–
|
|
|
3
|
Janus Henderson Investors US
Denver,
Colorado
|
$23.6M
|
+$14.3M
|
+80,965
|
+226%
|
|
|
4
|
VHCP Management II
New York
|
$19.5M
|
–
|
–
|
–
|
|
|
5
|
Eagle Asset Management
St Petersburg,
Florida
|
$8.25M
|
-$483K
|
-2,730
|
-6%
|
|
|
6
|
Acuta Capital Partners
Redwood City,
California
|
$5.36M
|
+$1.28M
|
+7,245
|
+38%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.7M
|
+$2.19M
|
+12,407
|
+115%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$4.21M
|
+$1.78M
|
+10,072
|
+94%
|
|
|
9
|
Millennium Management
New York
|
$2.52M
|
+$438K
|
+2,479
|
+25%
|
|
|
10
|
Asset Management One
Tokyo,
Japan
|
$2.42M
|
-$120K
|
-677
|
-5%
|
|
|
11
|
Opaleye Management
Boston,
Massachusetts
|
$2.28M
|
+$359K
|
+2,030
|
+22%
|
|
|
12
|
Fidelity Investments
Boston,
Massachusetts
|
$2.11M
|
-$8.17M
|
-46,235
|
-82%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$1.6M
|
+$533K
|
+3,014
|
+62%
|
|
|
14
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.52M
|
–
|
–
|
–
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$1.5M
|
+$596K
|
+3,372
|
+83%
|
|
|
16
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.38M
|
+$550K
|
+3,111
|
+83%
|
|
|
17
|
Nexthera Capital
New York
|
$1.37M
|
+$1.2M
|
+6,792
|
New
|
|
|
18
|
|
$1.36M
|
–
|
–
|
–
|
|
|
19
|
|
$1.18M
|
-$37.5K
|
-212
|
-3%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$760K
|
+$74.8K
|
+423
|
+13%
|
|
|
21
|
BlackRock Investment Management
Wilmington,
Delaware
|
$658K
|
+$305K
|
+1,723
|
+113%
|
|
|
22
|
TIAA CREF Investment Management
New York
|
$476K
|
+$260K
|
+1,472
|
+167%
|
|
|
23
|
Raymond James Financial Services Advisors
St. Petersburg,
Florida
|
$465K
|
–
|
–
|
–
|
|
|
24
|
Bank of New York Mellon
New York
|
$457K
|
+$203K
|
+1,147
|
+103%
|
|
|
25
|
|
$453K
|
+$396K
|
+2,239
|
New
|
|
