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Vaxcyte

295 hedge funds and large institutions have $6.81B invested in Vaxcyte in 2025 Q4 according to their latest regulatory filings, with 61 funds opening new positions, 95 increasing their positions, 106 reducing their positions, and 45 closing their positions.

New
Increased
Maintained
Reduced
Closed

86% more funds holding in top 10

Funds holding in top 10: 713 (+6)

36% more first-time investments, than exits

New positions opened: 61 | Existing positions closed: 45

34% more capital invested

Capital invested by funds: $5.09B → $6.81B (+$1.72B)

3.91% more ownership

Funds ownership: 108.82%112.72% (+3.9%)

4% more funds holding

Funds holding: 285295 (+10)

10% less repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 106

41% less call options, than puts

Call options by funds: $6.32M | Put options by funds: $10.8M

Holders
295
Holders Change
+10
Holders Change %
+3.51%
% of All Funds
3.59%
Holding in Top 10
13
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+85.71%
% of All Funds
0.16%
New
61
Increased
95
Reduced
106
Closed
45
Calls
$6.32M
Puts
$10.8M
Net Calls
-$4.43M
Net Calls Change
-$21M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$638M +$59.2M +1,324,581 +11%
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$618M +$12.7M +282,985 +2%
Vanguard Group
3
Vanguard Group
Pennsylvania
$563M -$5.66M -126,467 -1%
T. Rowe Price Investment Management
4
T. Rowe Price Investment Management
Maryland
$521M +$133M +2,981,038 +36%
RCM
5
RA Capital Management
Massachusetts
$495M -$55.5M -1,241,392 -10%
BlackRock
6
BlackRock
New York
$473M +$13M +290,400 +3%
Wellington Management Group
7
Wellington Management Group
Massachusetts
$275M +$41.8M +933,539 +19%
State Street
8
State Street
Massachusetts
$230M +$8.68M +194,116 +4%
PBA
9
Paradigm Biocapital Advisors
New York
$188M +$12.7M +283,265 +7%
DTC
10
Deep Track Capital
Connecticut
$185M +$44.7M +1,000,000 +33%
D.E. Shaw & Co
11
D.E. Shaw & Co
New York
$168M -$29.5M -659,737 -15%
Westfield Capital Management
12
Westfield Capital Management
Massachusetts
$163M -$8.63M -192,998 -5%
KCM
13
Kynam Capital Management
New Jersey
$135M -$6.68M -149,253 -5%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$132M -$793K -17,735 -0.6%
Adage Capital Partners
15
Adage Capital Partners
Massachusetts
$79.6M +$62.3M +1,392,000 +418%
CP
16
Caligan Partners
New York
$78.7M +$76.2M +1,704,815 New
PCH
17
Polar Capital Holdings
United Kingdom
$77.2M +$56.2M +1,257,253 +303%
PBPIA
18
Pivotal bioVenture Partners Investment Advisor
California
$63.3M
MC
19
Maverick Capital
Texas
$62.5M +$2.89M +64,670 +5%
Charles Schwab
20
Charles Schwab
California
$59.7M +$18.9K +423 +0%
Norges Bank
21
Norges Bank
Norway
$56.7M +$55M +1,228,939 New
EP
22
Eversept Partners
New York
$55.3M -$10M -224,261 -16%
T. Rowe Price Associates
23
T. Rowe Price Associates
Maryland
$54.2M -$23M -513,144 -30%
UBS Group
24
UBS Group
Switzerland
$50.5M +$11M +246,020 +29%
JP Morgan Chase
25
JP Morgan Chase
New York
$50.1M -$21.4M -479,517 -31%