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Vaxcyte

294 hedge funds and large institutions have $4.8B invested in Vaxcyte in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 132 increasing their positions, 76 reducing their positions, and 75 closing their positions.

New
Increased
Maintained
Reduced
Closed

124% more call options, than puts

Call options by funds: $12M | Put options by funds: $5.37M

74% more repeat investments, than reductions

Existing positions increased: 132 | Existing positions reduced: 76

14% more funds holding in top 10

Funds holding in top 10: 78 (+1)

1.04% more ownership

Funds ownership: 113.3%114.35% (+1%)

7% less funds holding

Funds holding: 315294 (-21)

18% less capital invested

Capital invested by funds: $5.88B → $4.8B (-$1.09B)

24% less first-time investments, than exits

New positions opened: 57 | Existing positions closed: 75

Holders
294
Holders Change
-21
Holders Change %
-6.67%
% of All Funds
3.87%
Holding in Top 10
8
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+14.29%
% of All Funds
0.11%
New
57
Increased
132
Reduced
76
Closed
75
Calls
$12M
Puts
$5.37M
Net Calls
+$6.65M
Net Calls Change
+$2.33M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$478M +$95.9M +2,925,863 +25%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$395M -$11.8M -361,184 -3%
Vanguard Group
3
Vanguard Group
Pennsylvania
$390M -$1.53M -46,720 -0.4%
RCM
4
RA Capital Management
Massachusetts
$389M -$7.32M -223,158 -2%
BlackRock
5
BlackRock
New York
$346M +$2.06M +62,766 +0.6%
T. Rowe Price Investment Management
6
T. Rowe Price Investment Management
Maryland
$195M +$108M +3,298,433 +122%
Wellington Management Group
7
Wellington Management Group
Massachusetts
$161M -$47.9M -1,462,126 -23%
State Street
8
State Street
Massachusetts
$161M +$17.5M +534,552 +12%
Capital Research Global Investors
9
Capital Research Global Investors
California
$155M -$43.9M -1,338,322 -22%
PBA
10
Paradigm Biocapital Advisors
New York
$110M +$55M +1,676,356 +99%
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$103M -$12.2M -371,760 -10%
D.E. Shaw & Co
12
D.E. Shaw & Co
New York
$100M +$72.8M +2,220,559 +256%
KCM
13
Kynam Capital Management
New Jersey
$99.9M -$4.21M -128,412 -4%
Westfield Capital Management
14
Westfield Capital Management
Massachusetts
$99.8M +$30M +913,761 +42%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$97.9M +$4.66M +142,086 +5%
DTC
16
Deep Track Capital
Connecticut
$69.9M +$45.9M +1,400,000 +187%
Charles Schwab
17
Charles Schwab
California
$46.1M +$2.76M +84,329 +6%
Jennison Associates
18
Jennison Associates
New York
$45.5M +$8.97M +273,579 +24%
UBS Group
19
UBS Group
Switzerland
$44.9M +$9.85M +300,457 +28%
MC
20
Maverick Capital
Texas
$42.6M +$3.36M +102,512 +8%
PBPIA
21
Pivotal bioVenture Partners Investment Advisor
California
$42.4M +$19.5M +594,391 +84%
EP
22
Eversept Partners
New York
$42.2M +$24.3M +741,444 +133%
JP Morgan Chase
23
JP Morgan Chase
New York
$39M -$23M -701,409 -37%
Pictet Asset Management
24
Pictet Asset Management
Switzerland
$38.2M +$4.1M +124,983 +12%
Northern Trust
25
Northern Trust
Illinois
$36.5M -$34.9K -1,064 -0.1%

PCVX Hedge Fund Activity: Q2 2025 in Review

294 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q2 2025, worth a combined $4.8B — down 18% from $5.88B a quarter earlier.

Sellers outnumbered buyers: 75 funds closed out of PCVX and 57 opened new positions — a net loss of 18 holders — while 76 trimmed existing stakes and 132 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $108M. The largest seller was Franklin Resources, cutting an estimated $70.5M.

  • 294 institutional investors held Vaxcyte (PCVX) as of Q2 2025, down from 315 in Q1 2025.
  • Funds reported $4.8B of Vaxcyte stock for Q2 2025, down 18% quarter-over-quarter.
  • 57 funds opened new Vaxcyte positions in Q2 2025 and 75 closed out, a net change of -18 holders.
  • The largest Vaxcyte buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $108M added.
  • The largest Vaxcyte seller in Q2 2025 was Franklin Resources, an estimated $70.5M sold.

Based on aggregated 13F filings for Q2 2025.