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Vaxcyte

285 hedge funds and large institutions have $5.09B invested in Vaxcyte in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 100 increasing their positions, 103 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

389% more call options, than puts

Call options by funds: $20.9M | Put options by funds: $4.27M

6% more capital invested

Capital invested by funds: $4.8B → $5.09B (+$292M)

3% less repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 103

9% less first-time investments, than exits

New positions opened: 40 | Existing positions closed: 44

3% less funds holding

Funds holding: 294285 (-9)

5.53% less ownership

Funds ownership: 114.35%108.82% (-5.5%)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

Holders
285
Holders Change
-9
Holders Change %
-3.06%
% of All Funds
3.74%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
40
Increased
100
Reduced
103
Closed
44
Calls
$20.9M
Puts
$4.27M
Net Calls
+$16.6M
Net Calls Change
+$9.96M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$472M -$52.6M -1,587,141 -11%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$451M +$11.9M +358,883 +3%
Vanguard Group
3
Vanguard Group
Pennsylvania
$444M +$10.7M +323,368 +3%
RCM
4
RA Capital Management
Massachusetts
$431M
BlackRock
5
BlackRock
New York
$359M -$22.7M -686,265 -6%
T. Rowe Price Investment Management
6
T. Rowe Price Investment Management
Maryland
$300M +$76.7M +2,314,171 +39%
Wellington Management Group
7
Wellington Management Group
Massachusetts
$181M +$2.58M +77,967 +2%
State Street
8
State Street
Massachusetts
$172M -$5.18M -156,346 -3%
D.E. Shaw & Co
9
D.E. Shaw & Co
New York
$155M +$39.8M +1,202,340 +39%
PBA
10
Paradigm Biocapital Advisors
New York
$136M +$13.6M +411,918 +12%
Westfield Capital Management
11
Westfield Capital Management
Massachusetts
$134M +$22M +663,817 +22%
KCM
12
Kynam Capital Management
New Jersey
$111M
DTC
13
Deep Track Capital
Connecticut
$108M +$28.2M +850,000 +40%
Geode Capital Management
14
Geode Capital Management
Massachusetts
$104M -$4.21M -127,100 -4%
T. Rowe Price Associates
15
T. Rowe Price Associates
Maryland
$60.8M -$49.1M -1,481,764 -47%
JP Morgan Chase
16
JP Morgan Chase
New York
$56.4M +$12.1M +366,266 +31%
EP
17
Eversept Partners
New York
$51.2M +$4.09M +123,469 +10%
PBPIA
18
Pivotal bioVenture Partners Investment Advisor
California
$49.4M +$2.23M +67,300 +5%
Charles Schwab
19
Charles Schwab
California
$46.6M -$4.12M -124,304 -9%
MC
20
Maverick Capital
Texas
$46.5M -$697K -21,038 -2%
Jennison Associates
21
Jennison Associates
New York
$42.2M -$7.57M -228,400 -16%
Northern Trust
22
Northern Trust
Illinois
$38.7M -$1.61M -48,546 -4%
Pictet Asset Management
23
Pictet Asset Management
Switzerland
$37.1M -$4.84M -146,032 -12%
Goldman Sachs
24
Goldman Sachs
New York
$35.1M +$1.35M +40,709 +4%
Royal Bank of Canada
25
Royal Bank of Canada
Ontario, Canada
$34.2M +$6.61M +199,657 +27%

PCVX Hedge Fund Activity: Q3 2025 in Review

285 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q3 2025, worth a combined $5.09B — up 6.1% from $4.8B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of PCVX and 40 opened new positions — a net loss of 4 holders — while 103 trimmed existing stakes and 100 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $76.7M. The largest seller was Capital Research Global Investors, cutting an estimated $130M.

  • 285 institutional investors held Vaxcyte (PCVX) as of Q3 2025, down from 294 in Q2 2025.
  • Funds reported $5.09B of Vaxcyte stock for Q3 2025, up 6.1% quarter-over-quarter.
  • 40 funds opened new Vaxcyte positions in Q3 2025 and 44 closed out, a net change of -4 holders.
  • The largest Vaxcyte buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $76.7M added.
  • The largest Vaxcyte seller in Q3 2025 was Capital Research Global Investors, an estimated $130M sold.

Based on aggregated 13F filings for Q3 2025.