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Vaxcyte

315 hedge funds and large institutions have $5.88B invested in Vaxcyte in 2025 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 129 increasing their positions, 98 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $14.1M | Put options by funds: $9.79M

32% more repeat investments, than reductions

Existing positions increased: 129 | Existing positions reduced: 98

0.35% more ownership

Funds ownership: 112.96%113.3% (+0.35%)

8% less first-time investments, than exits

New positions opened: 58 | Existing positions closed: 63

2% less funds holding

Funds holding: 323315 (-8)

42% less funds holding in top 10

Funds holding in top 10: 127 (-5)

49% less capital invested

Capital invested by funds: $11.5B → $5.88B (-$5.64B)

Holders
315
Holders Change
-8
Holders Change %
-2.48%
% of All Funds
4.22%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
58
Increased
129
Reduced
98
Closed
63
Calls
$14.1M
Puts
$9.79M
Net Calls
+$4.32M
Net Calls Change
-$18.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$816M +$95.2M +1,190,118 +11%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$472M -$46.3M -579,414 -4%
RCM
3
RA Capital Management
Massachusetts
$460M +$280M +3,499,959 +40%
Vanguard Group
4
Vanguard Group
Pennsylvania
$455M +$6.57M +82,118 +0.7%
BlackRock
5
BlackRock
New York
$399M -$42.1M -526,592 -5%
Wellington Management Group
6
Wellington Management Group
Massachusetts
$242M +$158M +1,972,918 +44%
Capital Research Global Investors
7
Capital Research Global Investors
California
$231M -$8.03M -100,415 -2%
State Street
8
State Street
Massachusetts
$166M -$10.5M -131,723 -3%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$134M -$34M -424,949 -11%
KCM
10
Kynam Capital Management
New Jersey
$121M +$69M +863,204 +37%
Franklin Resources
11
Franklin Resources
California
$117M +$17.6M +219,700 +8%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$108M +$5.29M +66,166 +2%
T. Rowe Price Investment Management
13
T. Rowe Price Investment Management
Maryland
$102M -$12.6M -158,026 -6%
Westfield Capital Management
14
Westfield Capital Management
Massachusetts
$81.4M -$32.9M -411,622 -16%
JP Morgan Chase
15
JP Morgan Chase
New York
$71.8M +$13.2M +164,516 +9%
AllianceBernstein
16
AllianceBernstein
Tennessee
$64.4M -$6.01M -75,151 -4%
PBA
17
Paradigm Biocapital Advisors
New York
$64.1M +$21.9M +273,694 +19%
CC
18
Commodore Capital
New York
$62.3M +$2M +25,000 +2%
Charles Schwab
19
Charles Schwab
California
$50.3M -$671K -8,391 -0.6%
Invesco
20
Invesco
Georgia
$47.4M +$7.18M +89,773 +8%
ClearBridge Investments
21
ClearBridge Investments
New York
$46.1M +$9.43M +117,969 +11%
MC
22
Maverick Capital
Texas
$45.6M +$495K +6,195 +0.5%
Deutsche Bank
23
Deutsche Bank
Germany
$45.2M -$1.2M -15,018 -1%
Goldman Sachs
24
Goldman Sachs
New York
$43.3M -$158M -1,982,302 -63%
Jennison Associates
25
Jennison Associates
New York
$42.5M -$9.66M -120,831 -10%

PCVX Hedge Fund Activity: Q1 2025 in Review

315 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q1 2025, worth a combined $5.88B — down 49% from $11.5B a quarter earlier.

Sellers outnumbered buyers: 63 funds closed out of PCVX and 58 opened new positions — a net loss of 5 holders — while 98 trimmed existing stakes and 129 added.

The largest buyer was RA Capital Management, adding an estimated $280M. The largest seller was Goldman Sachs, cutting an estimated $158M.

  • 315 institutional investors held Vaxcyte (PCVX) as of Q1 2025, down from 323 in Q4 2024.
  • Funds reported $5.88B of Vaxcyte stock for Q1 2025, down 49% quarter-over-quarter.
  • 58 funds opened new Vaxcyte positions in Q1 2025 and 63 closed out, a net change of -5 holders.
  • The largest Vaxcyte buyer in Q1 2025 was RA Capital Management, an estimated $280M added.
  • The largest Vaxcyte seller in Q1 2025 was Goldman Sachs, an estimated $158M sold.

Based on aggregated 13F filings for Q1 2025.