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Vaxcyte

285 hedge funds and large institutions have $5.09B invested in Vaxcyte in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 100 increasing their positions, 103 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

389% more call options, than puts

Call options by funds: $20.9M | Put options by funds: $4.27M

6% more capital invested

Capital invested by funds: $4.8B → $5.09B (+$292M)

3% less repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 103

9% less first-time investments, than exits

New positions opened: 40 | Existing positions closed: 44

3% less funds holding

Funds holding: 294285 (-9)

5.53% less ownership

Funds ownership: 114.35%108.82% (-5.5%)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

Holders
285
Holders Change
-9
Holders Change %
-3.06%
% of All Funds
3.74%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
40
Increased
100
Reduced
103
Closed
44
Calls
$20.9M
Puts
$4.27M
Net Calls
+$16.6M
Net Calls Change
+$9.96M
Name Holding Trade Value Shares
Change
Change in
Stake
SBH
76
Segall Bryant & Hamill
Illinois
$6.66M +$151K +4,556 +3%
RhumbLine Advisers
77
RhumbLine Advisers
Massachusetts
$6.6M -$506K -15,275 -8%
Invesco
78
Invesco
Georgia
$6.45M +$578K +17,445 +11%
CAM
79
Cormorant Asset Management
Massachusetts
$6.3M
AG
80
Algert Global
California
$6.2M +$748K +22,570 +15%
Rafferty Asset Management
81
Rafferty Asset Management
New York
$5.38M -$511K -15,409 -9%
California Public Employees Retirement System
82
California Public Employees Retirement System
California
$5.21M -$247K -7,463 -5%
Manulife (Manufacturers Life Insurance)
83
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$4.93M -$2.36M -71,140 -34%
AllianceBernstein
84
AllianceBernstein
Tennessee
$4.87M -$207K -6,260 -4%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
85
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$4.86M +$4.47M +134,877 New
Legal & General Group
86
Legal & General Group
United Kingdom
$4.7M -$105K -3,161 -2%
BFM
87
Boothbay Fund Management
New York
$4.64M +$844K +25,464 +25%
Wells Fargo
88
Wells Fargo
California
$4.54M +$158K +4,763 +4%
ACM
89
Aquatic Capital Management
Illinois
$4.53M -$2.66M -80,386 -39%
AAA
90
Affinity Asset Advisors
New York
$4.5M
New York State Common Retirement Fund
91
New York State Common Retirement Fund
New York
$4.39M -$109K -3,300 -3%
TI
92
Trexquant Investment
Connecticut
$4.32M +$450K +13,569 +13%
Lazard Asset Management
93
Lazard Asset Management
New York
$4.29M -$13M -393,043 -77%
Susquehanna International Group
94
Susquehanna International Group
Pennsylvania
$4.28M -$1.13M -34,118 -22%
EGM
95
Engineers Gate Manager
New York
$4.13M -$1.53M -46,148 -29%
HF
96
HRT Financial
New York
$4.11M +$3.78M +114,034 New
California State Teachers Retirement System (CalSTRS)
97
California State Teachers Retirement System (CalSTRS)
California
$3.94M +$79.3K +2,394 +2%
Two Sigma Investments
98
Two Sigma Investments
New York
$3.88M +$663K +20,025 +23%
NFT
99
Nan Fung Trinity
Hong Kong
$3.76M
CSS
100
Cubist Systematic Strategies
Connecticut
$3.62M +$3.33M +100,561 New

PCVX Hedge Fund Activity: Q3 2025 in Review

285 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q3 2025, worth a combined $5.09B — up 6.1% from $4.8B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of PCVX and 40 opened new positions — a net loss of 4 holders — while 103 trimmed existing stakes and 100 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $76.7M. The largest seller was Capital Research Global Investors, cutting an estimated $130M.

  • 285 institutional investors held Vaxcyte (PCVX) as of Q3 2025, down from 294 in Q2 2025.
  • Funds reported $5.09B of Vaxcyte stock for Q3 2025, up 6.1% quarter-over-quarter.
  • 40 funds opened new Vaxcyte positions in Q3 2025 and 44 closed out, a net change of -4 holders.
  • The largest Vaxcyte buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $76.7M added.
  • The largest Vaxcyte seller in Q3 2025 was Capital Research Global Investors, an estimated $130M sold.

Based on aggregated 13F filings for Q3 2025.