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Vaxcyte

315 hedge funds and large institutions have $5.88B invested in Vaxcyte in 2025 Q1 according to their latest regulatory filings, with 58 funds opening new positions, 129 increasing their positions, 98 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

44% more call options, than puts

Call options by funds: $14.1M | Put options by funds: $9.79M

32% more repeat investments, than reductions

Existing positions increased: 129 | Existing positions reduced: 98

0.35% more ownership

Funds ownership: 112.96%113.3% (+0.35%)

8% less first-time investments, than exits

New positions opened: 58 | Existing positions closed: 63

2% less funds holding

Funds holding: 323315 (-8)

42% less funds holding in top 10

Funds holding in top 10: 127 (-5)

49% less capital invested

Capital invested by funds: $11.5B → $5.88B (-$5.64B)

Holders
315
Holders Change
-8
Holders Change %
-2.48%
% of All Funds
4.22%
Holding in Top 10
7
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-41.67%
% of All Funds
0.09%
New
58
Increased
129
Reduced
98
Closed
63
Calls
$14.1M
Puts
$9.79M
Net Calls
+$4.32M
Net Calls Change
-$18.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Barclays
76
Barclays
United Kingdom
$8.54M -$2.3M -28,763 -11%
DM
77
Deerfield Management
New York
$8.5M
Victory Capital Management
78
Victory Capital Management
Texas
$8.34M -$6.62M -82,737 -27%
Swiss National Bank
79
Swiss National Bank
Switzerland
$8.21M -$136K -1,700 -0.8%
IC
80
Ikarian Capital
Texas
$7.55M +$16M +200,000 New
Russell Investments Group
81
Russell Investments Group
United Kingdom
$7.54M +$7.29M +91,201 +84%
Renaissance Technologies
82
Renaissance Technologies
New York
$7.41M +$11.4M +142,200 +263%
Macquarie Group
83
Macquarie Group
Australia
$7.17M -$4.66M -58,241 -23%
SEI Investments
84
SEI Investments
Pennsylvania
$6.87M +$1.62M +20,221 +13%
RhumbLine Advisers
85
RhumbLine Advisers
Massachusetts
$6.84M +$753K +9,416 +5%
CAM
86
Cormorant Asset Management
Massachusetts
$6.61M -$20M -250,000 -59%
Alyeska Investment Group
87
Alyeska Investment Group
Illinois
$6.22M -$2.63M -32,945 -17%
Manulife (Manufacturers Life Insurance)
88
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$5.78M -$430K -5,376 -3%
SBH
89
Segall Bryant & Hamill
Illinois
$5.66M -$338K -4,226 -3%
Jane Street
90
Jane Street
New York
$5.49M -$12.3M -153,903 -51%
Hudson Bay Capital Management
91
Hudson Bay Capital Management
Connecticut
$5.45M +$3.64M +45,570 +46%
California Public Employees Retirement System
92
California Public Employees Retirement System
California
$5.39M -$3.62M -45,304 -24%
New York State Common Retirement Fund
93
New York State Common Retirement Fund
New York
$5.19M +$7.21M +90,145 +191%
Rafferty Asset Management
94
Rafferty Asset Management
New York
$4.98M -$1.25M -15,624 -11%
WCM Investment Management
95
WCM Investment Management
California
$4.96M -$49.3K -617 -0.9%
Legal & General Group
96
Legal & General Group
United Kingdom
$4.9M +$496K +6,208 +5%
Prudential Financial
97
Prudential Financial
New Jersey
$4.77M -$108K -1,355 -1%
Schroder Investment Management Group
98
Schroder Investment Management Group
United Kingdom
$4.59M +$1.7M +21,298 +48%
NIP
99
Nicholas Investment Partners
California
$4.39M +$1.27M +15,922 +16%
GPP
100
Great Point Partners
Connecticut
$4.36M +$9.24M +115,517 New

PCVX Hedge Fund Activity: Q1 2025 in Review

315 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q1 2025, worth a combined $5.88B — down 49% from $11.5B a quarter earlier.

Sellers outnumbered buyers: 63 funds closed out of PCVX and 58 opened new positions — a net loss of 5 holders — while 98 trimmed existing stakes and 129 added.

The largest buyer was RA Capital Management, adding an estimated $280M. The largest seller was Goldman Sachs, cutting an estimated $158M.

  • 315 institutional investors held Vaxcyte (PCVX) as of Q1 2025, down from 323 in Q4 2024.
  • Funds reported $5.88B of Vaxcyte stock for Q1 2025, down 49% quarter-over-quarter.
  • 58 funds opened new Vaxcyte positions in Q1 2025 and 63 closed out, a net change of -5 holders.
  • The largest Vaxcyte buyer in Q1 2025 was RA Capital Management, an estimated $280M added.
  • The largest Vaxcyte seller in Q1 2025 was Goldman Sachs, an estimated $158M sold.

Based on aggregated 13F filings for Q1 2025.