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Vaxcyte

285 hedge funds and large institutions have $5.09B invested in Vaxcyte in 2025 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 100 increasing their positions, 103 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

389% more call options, than puts

Call options by funds: $20.9M | Put options by funds: $4.27M

6% more capital invested

Capital invested by funds: $4.8B → $5.09B (+$292M)

3% less repeat investments, than reductions

Existing positions increased: 100 | Existing positions reduced: 103

9% less first-time investments, than exits

New positions opened: 40 | Existing positions closed: 44

3% less funds holding

Funds holding: 294285 (-9)

5.53% less ownership

Funds ownership: 114.35%108.82% (-5.5%)

13% less funds holding in top 10

Funds holding in top 10: 87 (-1)

Holders
285
Holders Change
-9
Holders Change %
-3.06%
% of All Funds
3.74%
Holding in Top 10
7
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-12.5%
% of All Funds
0.09%
New
40
Increased
100
Reduced
103
Closed
44
Calls
$20.9M
Puts
$4.27M
Net Calls
+$16.6M
Net Calls Change
+$9.96M
Name Holding Trade Value Shares
Change
Change in
Stake
Ameriprise
51
Ameriprise
Minnesota
$13.5M +$1.47M +44,231 +13%
Fiera Capital (Canada)
52
Fiera Capital (Canada)
Quebec, Canada
$12.5M -$265K -7,990 -2%
American Century Companies
53
American Century Companies
Missouri
$12.4M -$233K -7,025 -2%
Jane Street
54
Jane Street
New York
$12.4M +$1.52M +45,949 +15%
Franklin Resources
55
Franklin Resources
California
$12.1M -$20M -603,169 -64%
Adage Capital Partners
56
Adage Capital Partners
Massachusetts
$12M +$11M +333,000 New
Victory Capital Management
57
Victory Capital Management
Texas
$11.3M -$4.5M -135,727 -30%
SCM
58
Silverarc Capital Management
Massachusetts
$11.3M +$879K +26,543 +9%
Citigroup
59
Citigroup
New York
$11.3M -$3.85M -116,206 -27%
IC
60
Ikarian Capital
Texas
$11.2M +$221K +6,682 +2%
TCM
61
Tang Capital Management
California
$10.8M
Balyasny Asset Management
62
Balyasny Asset Management
Illinois
$10M +$5.74M +173,297 +165%
BNP Paribas Financial Markets
63
BNP Paribas Financial Markets
France
$9.28M +$3.93M +118,543 +85%
WP
64
Woodline Partners
California
$8.9M +$1.55M +46,908 +23%
Man Group
65
Man Group
United Kingdom
$8.82M +$7.14M +215,402 +730%
Alyeska Investment Group
66
Alyeska Investment Group
Illinois
$8.82M
TC
67
TwinBeech Capital
New York
$8.22M -$9.12M -275,161 -55%
Swiss National Bank
68
Swiss National Bank
Switzerland
$8.11M +$126K +3,800 +2%
Assenagon Asset Management
69
Assenagon Asset Management
Luxembourg
$7.92M +$5.7M +171,974 +358%
DP
70
Diadema Partners
New Jersey
$7.86M +$663K +20,000 +10%
ACM
71
ADAR1 Capital Management
Texas
$7.67M +$3.81M +115,032 +117%
Citadel Advisors
72
Citadel Advisors
Florida
$7.41M -$29.3M -884,939 -81%
CWG
73
C WorldWide Group
Denmark
$7.02M
JF
74
Jump Financial
Illinois
$6.91M -$7.02M -211,897 -53%
Raymond James Financial
75
Raymond James Financial
Florida
$6.82M -$3.65M -110,289 -37%

PCVX Hedge Fund Activity: Q3 2025 in Review

285 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Vaxcyte (PCVX) for Q3 2025, worth a combined $5.09B — up 6.1% from $4.8B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of PCVX and 40 opened new positions — a net loss of 4 holders — while 103 trimmed existing stakes and 100 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $76.7M. The largest seller was Capital Research Global Investors, cutting an estimated $130M.

  • 285 institutional investors held Vaxcyte (PCVX) as of Q3 2025, down from 294 in Q2 2025.
  • Funds reported $5.09B of Vaxcyte stock for Q3 2025, up 6.1% quarter-over-quarter.
  • 40 funds opened new Vaxcyte positions in Q3 2025 and 44 closed out, a net change of -4 holders.
  • The largest Vaxcyte buyer in Q3 2025 was T. Rowe Price Investment Management, an estimated $76.7M added.
  • The largest Vaxcyte seller in Q3 2025 was Capital Research Global Investors, an estimated $130M sold.

Based on aggregated 13F filings for Q3 2025.